Gabriele Pollara · @gpollara
621 followers · 1082 posts · Server med-mastodon.com
How the inflammasome is activated. Almost poetic seeing it in step-wise motion here...
Cryo-EM structures of the active NLRP3 inflammasome disc - https://www.nature.com/articles/s41586-022-05570-8?WT.ec_id=NATURE-20230119&utm_source=nature_etoc&utm_medium=email&utm_campaign=20230119&sap-outbound-id=1540E81EA8A2575BEBC0E3AB32A3412AEAC13A1D
#immunology #cells '#academia #Science #IL1 #inflammasome #infection #cellular #EM
#immunology #cells #academia #Science #il1 #inflammasome #infection #cellular #em
Gabriele Pollara · @gpollara
461 followers · 535 posts · Server med-mastodon.comThe IL-1 cytokine family continues to amaze with its complexity.
Here IL-37 cleaved by neutrophil elastase 👉 bind to IL-36 receptor 👉 inflammation.