#IDMastodon #Immmunology #CellImmunity #InnateImmunity @JEM Inherited MyD88 & IRAK-4 deficiencies are predisposed to #hypoxemic #COVID19 . The patients’ susceptibility to #SarsCoV2 can be attributed to impaired TLR7-dependent type I IFN production by pDCs, which do not sense #SARSCoV2 correctly
📌 https://rupress.org/jem/article/220/5/e20220170/213920/Humans-with-inherited-MyD88-and-IRAK-4
📌 https://rupress.org/jem/issue
#IDMastodon #immmunology #cellimmunity #innateimmunity #hypoxemic #COVID19 #SarsCoV2