The EMBO Journal · @embojournal
525 followers · 260 posts · Server sciencemastodon.com
Extra #centrosomes are initially anti-#tumorigenic but why?
Irmina Garcia-Carpio, Andreas Villunger et al find that through #PIDDosome activation, they not only induce #p53 responses, but also #NFkB signaling to increase #immunogenicity of cancer cells
https://www.embopress.org/doi/full/10.15252/embj.2023113510
#centrosomes #tumorigenic #piddosome #P53 #nfkb #immunogenicity
Giuseppe Michieli · @GMIK69
72 followers · 1596 posts · Server mstdn.science[Articles] #Safety and #immunogenicity of a purified inactivated #Zika virus #vaccine candidate in adults primed with a Japanese encephalitis virus or yellow fever virus vaccine in the #USA: a phase 1, randomised, double-blind, placebo-controlled clinical trial https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00192-5/fulltext?rss=yes #EID #research #arbovirus
#safety #immunogenicity #zika #vaccine #usa #eid #research #arbovirus
Giuseppe Michieli · @GMIK69
67 followers · 1332 posts · Server mstdn.science#Safety, #immunogenicity, and #efficacy of the #mRNA #vaccine CS-2034 as a heterologous #booster versus homologous booster with BBIBP-CorV in adults aged ≥18 years: a randomised, double-blind, phase 2b trial, DOI:https://doi.org/10.1016/S1473-3099(23)00199-8
#safety #immunogenicity #efficacy #mrna #vaccine #booster
Giuseppe Michieli · @GMIK69
68 followers · 1317 posts · Server mstdn.science[Articles] #Safety and #immunogenicity of heterologous boosting with orally aerosolised or intramuscular Ad5-nCoV #vaccine and homologous boosting with inactivated vaccines (BBIBP-CorV or CoronaVac) in children and adolescents: a randomised, open-label, parallel-controlled, non-inferiority, single-centre study https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00129-7/fulltext?rss=yes
#safety #immunogenicity #vaccine
Giuseppe Michieli · @GMIK69
59 followers · 1133 posts · Server mstdn.science[Articles] #Immunogenicity of #bivalent #omicron (BA.1) #booster #vaccination after different priming regimens in #HCWs in the #Netherlands (SWITCH ON): results from the direct boost group of an open-label, multicentre, randomised controlled trial https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00140-8/fulltext?rss=yes
#immunogenicity #bivalent #omicron #booster #vaccination #hcws #Netherlands
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.science[Articles] #Safety and #immunogenicity of aerosolised Ad5-nCoV, intramuscular Ad5-nCoV, or inactivated #COVID19 #vaccine #CoronaVac given as the second #booster following three doses of CoronaVac: a multicentre, open-label, phase 4, randomised trial https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00049-8/fulltext?rss=yes
#safety #immunogenicity #COVID19 #vaccine #coronavac #booster
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.science#Immunogenicity and #protection of a #variant nanoparticle #vaccine that confers broad #neutralization against #SARS-CoV-2 variants https://www.nature.com/articles/s41467-022-35606-6
#immunogenicity #protection #variant #vaccine #neutralization #sars
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.scienceCarbohydrate fatty acid monosulphate: #oil-in-water #adjuvant enhances #SARS-CoV-2 #RBD nanoparticle-induced #immunogenicity and #protection in mice https://www.nature.com/articles/s41541-023-00610-4
#oil #adjuvant #sars #rbd #immunogenicity #protection
Giuseppe Michieli · @GMIK69
54 followers · 969 posts · Server mstdn.scienceSafety, tolerability, and #immunogenicity of the chimpanzee #adenovirus type 3-vectored #Marburg virus (cAd3-Marburg) #vaccine in healthy adults in the #USA: a first-in-human, phase 1, open-label, dose-escalation trial https://www.sciencedirect.com/science/article/pii/S014067362202400X?dgcid=rss_sd_all
#immunogenicity #adenovirus #marburg #vaccine #usa
Giuseppe Michieli · @GMIK69
54 followers · 969 posts · Server mstdn.science#Immunogenicity of a Fourth Homologous Dose of NVX-CoV2373 #vaccine, NEJM: https://www.nejm.org/doi/full/10.1056/NEJMc2215509?query=TOC&cid=NEJM%20eToc,%20January%2026,%202023%20DM1931502_NEJM_Non_Subscriber&bid=1379403247
Giuseppe Michieli · @GMIK69
54 followers · 969 posts · Server mstdn.science[Articles] The #safety and #immunogenicity of two #Zika virus #mRNA #vaccine candidates in healthy #flavivirus baseline seropositive and seronegative adults: the results of two randomised, placebo-controlled, dose-ranging, phase 1 clinical trials https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00764-2/fulltext?rss=yes
#safety #immunogenicity #zika #mrna #vaccine #Flavivirus
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.science
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.scienceComparison of #humoral #immunogenicity in solid organ #transplant recipients after third-dose #mRNA #vaccine with homologous or heterologous schedules: an observational study, https://doi.org/10.1016/j.jcv.2022.105374
#humoral #immunogenicity #transplant #mrna #vaccine
Maia · @Maia
49 followers · 1064 posts · Server mastodon.online
RT @NewsMedical@twitter.com
@medrxivpreprint@twitter.com Safety and immunogenicity of the Omicron BA.4/BA.5-containing bivalent booster mRNA-1273.222 https://www.news-medical.net/news/20221219/Safety-and-immunogenicity-of-the-Omicron-BA4BA5-containing-bivalent-booster-mRNA-1273222.aspx @medrxivpreprint@twitter.com @BrighamWomens@twitter.com @MeridianClinRes@twitter.com #immunogenicity #Omicron #mRNA #COVID19 #coronavirus #covid #SARSCoV2
#sarscov2 #covid #Coronavirus #COVID19 #mrna #Omicron #immunogenicity
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.scienceLiu, L.TC., Chiu, CH., Chiu, NC. et al. #Safety and #immunogenicity of #SARS-CoV-2 #vaccine MVC-COV1901 in #Taiwanese #adolescents: a randomized phase 2 trial. npj Vaccines 7, 165 (2022). https://doi.org/10.1038/s41541-022-00589-4
#safety #immunogenicity #sars #vaccine #Taiwanese #adolescents
Giuseppe Michieli · @GMIK69
54 followers · 970 posts · Server mstdn.scienceSafety and #immunogenicity of a ChAd155-vectored #RSV #vaccine (ChAd155-RSV) in healthy RSV-seropositive children 12–23 months of age, https://doi.org/10.1093/infdis/jiac481
Salva Iborra Lab · @Salva_Iborra_Lab
32 followers · 56 posts · Server mathstodon.xyzRT @eballestar@twitter.com
Happy to share our study showing #VitaminC boosting #immunogenicity properties of #DendriticCells through NF-κB- & #TET2 driven #DNAdemethylation @octaviompa@twitter.com @GerardGodoy3@twitter.com @JoseL_Sardina@twitter.com @Eva_M_C@twitter.com @CarrerasIJC@twitter.com https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac941/6777795
🐦🔗: https://twitter.com/eballestar/status/1587739956100812800
#dnademethylation #tet2 #dendriticcells #immunogenicity #vitaminc