TrangAston :verified: · @CastlTrAstonDrs
1441 followers · 3138 posts · Server med-mastodon.com
#IDMastodon #microbiology #BraingutAxis #Neuroimmunology lactate-induced HIF1α activation in the context of CNS #autoimmunity initiates a regulatory loop in DCs that limits #immunopathology.
#IDMastodon #microbiology #braingutaxis #neuroimmunology #autoimmunity #immunopathology
TrangAston :verified: · @CastlTrAstonDrs
1441 followers · 3135 posts · Server med-mastodon.com
#IDMastodon #BraingutAxis #Neuroimmunology @naturemedicine
lactate-induced HIF1α activation in the context of CNS #autoimmunity initiates a regulatory loop in DCs that limits #immunopathology.
#IDMastodon #braingutaxis #neuroimmunology #autoimmunity #immunopathology
TrangAston :verified: · @CastlTrAstonDrs
1336 followers · 2673 posts · Server med-mastodon.com
#IDMastodon #Clinicaltrials The #immunopathology of #COVID19 involves aberrant immune cell function and dysregulation of cytokine and chemokine networks. A randomized, double-masked, placebo-controlled master protocol clinical trial found that treatment with abatacept, cenicriviroc, or infliximab showed no statistically significant difference for the primary end point of time to recovery in patients with #COVID19 vs standard care.
https://jamanetwork.com/journals/jama/fullarticle/2807333
#IDMastodon #clinicaltrials #immunopathology #COVID19
Giuseppe Michieli · @GMIK69
73 followers · 1614 posts · Server mstdn.scienceImmunological #imprinting of humoral #immunity to #SARS-CoV-2 in #children https://www.nature.com/articles/s41467-023-39575-2 #immunology #immunopathology
#imprinting #immunity #sars #children #immunology #immunopathology
Gabriele Pollara · @gpollara
716 followers · 1621 posts · Server med-mastodon.comNice little study this, using SNPs in CCL19 & CCL21 linked with higher levels of these chemokines associated with greater #COVID19 infection and mortality.
Wonder if there's a mechanism. Greater #Neutrophil chemotaxis 👉 tissue pathology?
#IDMastodon #MedMastodon #immunopathology #immunology
CCL19 (rs3136658) and CCL21 (rs2812377) variants are associated with susceptibility and related mortality of SARS-CoV-2 infection: a population-based correlation analysis
https://academic.oup.com/jid/advance-article/doi/10.1093/infdis/jiad032/7022103
#COVID19 #neutrophil #IDMastodon #MedMastodon #immunopathology #immunology
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.scienceDistinct #tissue #niches direct #lung #immunopathology via #CCL18 and #CCL21 in severe #COVID19 https://www.nature.com/articles/s41467-023-36333-2
#tissue #niches #Lung #immunopathology #ccl18 #ccl21 #COVID19
Gabriele Pollara · @gpollara
679 followers · 1401 posts · Server med-mastodon.com
Didn't make the title, but higher IL-6 concentration associated with higher risk of hospitalisation.
(cause or effect 🤔)
#IDMastodon #MedMastodon #immunology #immunopathology #virology #virus #RSV
#IDMastodon #MedMastodon #immunology #immunopathology #virology #Virus #rsv
Gabriele Pollara · @gpollara
678 followers · 1399 posts · Server med-mastodon.comDidn't make the title, but higher IL-6 concentration associated with higher risk of hospitalisation.
(cause or effect 🤔)
#IDMastodon #MedMastodon #immunology #immunopathology
#IDMastodon #MedMastodon #immunology #immunopathology
TrangAston :verified: · @CastlTrAstonDrs
1033 followers · 1295 posts · Server med-mastodon.com
#IDMastodon @medrxivpreprint Recap #COVID19 #immunopathology: From acute diseases to chronic sequelae https://onlinelibrary.wiley.com/doi/full/10.1002/jmv.28122
#IDMastodon #COVID19 #immunopathology
TrangAston :verified: · @CastlTrAstonDrs
288 followers · 271 posts · Server med-mastodon.com@biorxivpreprint
📌 https://www.sciencedirect.com/science/article/pii/S1043466622002204
📌 https://pmj.bmj.com/content/98/1165/871
📌 https://f1000research.com/articles/11-1285
📌 https://europepmc.org/article/med/35074571
📌 https://www.journalofinfection.com/article/S0163-4453(22)00477-7/fulltext
📌 https://link.springer.com/article/10.1007/s12325-022-02042-3
The #immunology & #immunopathology of #COVID19 & #LongCovid
📌https://www.science.org/doi/full/10.1126/science.abm8108
#immunology #immunopathology #COVID19 #LongCovid
