TrangAston :verified: · @CastlTrAstonDrs
1353 followers · 2798 posts · Server med-mastodon.com
#IDMastodon #publichealth #Viralimmunology Understanding why we have different responses & symptoms to #SARSCoV2 ( #COVID19) & #influenza 🦠. What these 2 diseases have in common is that they are triggered by a viral infection, which causes fever & pneumonia of varying degrees of severity in infected patients. #Autoantibodies against #interferons, or why certain 🦠 affect us differently
https://rupress.org/jem/article/220/9/e20230661/214186/Autoantibodies-neutralizing-type-I-IFNs-underlie
#IDMastodon #publichealth #viralimmunology #SarsCoV2 #COVID19 #influenza #Autoantibodies #interferons
Giuseppe Michieli · @GMIK69
68 followers · 1474 posts · Server mstdn.scienceJacob RA, Zhang A, Ajoge HO, D’Agostino MR, Nirmalarajah K, Shigayeva A, et al. Sensitivity to neutralizing #antibodies and #resistance to type I #interferons in #SARS-CoV-2 #R1 lineage #variants, #Canada. Emerg Infect Dis. 2023 Jul [date cited]. https://doi.org/10.3201/eid2907.230198
#antibodies #resistance #interferons #sars #r1 #variants #canada
TrangAston :verified: · @CastlTrAstonDrs
1246 followers · 2319 posts · Server med-mastodon.com
#IDMastodon
#Viralimmunology #Immunology @casanova_lab et al Grat paper on Interfering with #interferons A Critical Mechanism for critical #COVID19 . Genetic studies in patients have established that critical cases can re- sult from inborn errors of TLR3- or TLR7-dependent type I interferon immunity, or from preexisting #autoantibodies neutralizing primarily IFN-α and/or IFN-ω.
https://www.annualreviews.org/doi/pdf/10.1146/annurev-immunol-101921-050835
#IDMastodon #viralimmunology #immunology #interferons #COVID19 #Autoantibodies
halama_immuno · @halama_immuno
260 followers · 1063 posts · Server mstdn.scienceWhen the immune system attacks the immune system: #Autoantibodies against #interferons (type I) have an impact on #immuneresponses and are associated with viral disease susceptibility as outlined in this elegant review... #immunology #virology #cytokines #infections #autoimmunity #immunoregulation
https://onlinelibrary.wiley.com/doi/abs/10.1002/eji.202250164
#autoantibodies #interferons #immuneresponses #immunology #virology #cytokines #infections #autoimmunity #immunoregulation
halama_immuno · @halama_immuno
259 followers · 1039 posts · Server mstdn.science@chfloudas It also brings up the question, what type of #ImmuneResponse delivers the best impact against the tumor bulk...suggestive of non-canonical responses beyond #interferons or synergistic #innateimmunity activation #immunology
#immuneresponse #interferons #innateimmunity #immunology
Achillebro👨🏼⚕️ · @Achillebro
110 followers · 48 posts · Server mstdn.science#introduction Hi y'all,
I am a CNRS researcher @CIML Marseille.
Mucosal immunologist, interested in gut biology, #interferons, #host_pathogen interaction, and #Organoids. URL: http://www.ciml.univ-mrs.fr/science/lab-achille-broggi/innate-immunity-mucosal-sites
#introduction #interferons #host_pathogen #organoids