The plasticitome of #cortical #interneurons
#neuroscience
https://doi.org/10.1038/s41583-022-00663-9
#cortical #interneurons #neuroscience
This looks worth reading through!
Cortical VIP neurons locally control the gain but globally control the coherence of gamma band rhythms #neuroscience #interneurons
https://doi.org/10.1016/j.neuron.2022.10.036
Next, https://onlinelibrary.wiley.com/doi/abs/10.1111/ejn.15866
Here authors go deep into slice #ephys to show cholinergic neuromodulation of #LC NAergic cells and periLC #interneurons, via muscarinic Ach receptors.
In an interesting twist, mAchR activation *both* increases spontaneous activity of the forementioned cell types, *and* suppresses inhibitory input to LC-NA neurons.
Data indicate that, in a receptor-specific manner, cholinergic neuromodulation alters E/I relations within the LC
Of mice and human interneurons: A Q&A with Moritz Helmstaedter
https://www.spectrumnews.org/opinion/q-and-a/of-mice-and-human-interneurons-a-qa-with-moritz-helmstaedter/
#inhibitorysignaling #signalingimbalance #neuralcircuits #interneurons #mousemodels #monkeys #autism #cortex #QA
#inhibitorysignaling #signalingimbalance #neuralcircuits #interneurons #mousemodels #monkeys #autism #Cortex #QA
Gene therapy targets interneurons to tackle Dravet syndrome
https://www.spectrumnews.org/news/gene-therapy-targets-interneurons-to-tackle-dravet-syndrome/
#interneurons #genetherapy #mousemodels #seizures #monkeys #autism #News #GABA
#interneurons #genetherapy #mousemodels #seizures #monkeys #autism #news #GABA
Mini biopsies point to source of lethal seizures in model mice
https://www.spectrumnews.org/news/mini-biopsies-point-to-source-of-lethal-seizures-in-model-mice/
#interneurons #ionchannels #mousemodels #seizures #synapses #autism #News
#interneurons #ionchannels #mousemodels #seizures #synapses #autism #news
Two groups of neurons govern autism-like traits in model mice
https://www.spectrumnews.org/news/two-groups-of-neurons-govern-autism-like-traits-in-model-mice/
#repetitivebehavior #geneexpression #neuralcircuits #socialdeficits #interneurons #mousemodels #striatum #autism #cancer #cortex #News
#repetitivebehavior #geneexpression #neuralcircuits #socialdeficits #interneurons #mousemodels #striatum #autism #cancer #Cortex #news