Joanna Masel · @JoannaMasel
1061 followers · 417 posts · Server ecoevo.socialOur preprint describes how #EffectivePopulationSize affects #AminoAcid usage. https://www.biorxiv.org/content/10.1101/2023.02.01.526552v2. Within highly exchangeable pairs of amino acids, high Ne species are able to prefer #arginine over #lysine, and #valine over #isoleucine. This matches #thermophile preferences, as expected from theories of marginal protein stability at mutation-selection-drift balance. 1/6
@hanonmcshea #NearlyNeutralTheory #MolecularEvolution #EvolgenPaper
#effectivepopulationsize #aminoAcid #arginine #lysine #valine #isoleucine #thermophile #nearlyneutraltheory #MolecularEvolution #evolgenpaper