new research article:
Nuclear lamina erosion-induced resurrection of endogenous retroviruses underlies neuronal aging

https://doi.org/10.1016/j.celrep.2023.112593

"we verified the loss of B-type lamins inducing resurrection of ERVs as an initiating event of the aging-bound cascade in post-mitotic neurons. Of significance, these aging-related cellular and molecular changes can be alleviated by abacavir"

#Brain #Aging #HERV #EndogenousRetrovirus
#laminB