A quadruple mutation in the human androgen receptor ligand-binding domain increases its soluble expression in complex with pruxelutamide in E. coli & reveals a partially open conformation @ActaCrystF @IUCr #AndrogenReceptors #LigandBindingDomain #DHT https://doi.org/10.1107/S2053230X23002224

Selom K. Doamekpor et al.: A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations #DHT #LigandBindingDomain ... #IUCr http://scripts.iucr.org/cgi-bin/paper?S2053230X23002224