#Sirt6 deacetylates #YAP & #TAZ->
⏬their transcriptional activities
⏬TGFβ1-induced Fibrotic reprogramming of #HepaticStellateCell
in diet-induced🐭#LiverFibrosis

TAZ seems more sensitive to Sirt6 than YAP🤓

#MALFD

Dr. Charlie Dong lab FASEB J 2022
https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202200522R

Referenced link: https://medicalxpress.com/news/2022-09-molecule-liver-fibrosis.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2022-09-molecule-liver-fibrosis.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/medical_xpress/status/1574507220255084545#m

RT by @physorg_com: This molecule could be behind #liverfibrosis @umich @NatureComms https://www.nature.com/articles/s41467-022-32575-8 https://medicalxpress.com/news/2022-09-molecule-liver-fibrosis.html