RT @SABOURETCardio
A step by step approach which still leads to therapeutic #inertia. When will they move from theoretical to efficient strategy? #LLT #recurrentEvents #ACS

RT @SABOURETCardio
Modulation and personalization of therapy after acute coronary syndromes... https://youtu.be/1PqXutMtZZI via @YouTube #DAPT De Escalation #LLT #UpfrontStrategy #SAPT #EHJ

RT @SABOURETCardio
I’m still surprised by the high number of #LLT #statins deniers despite the amount of proofs. But we still try to support a better management of #ASCVD patients despite toxic people. “Ignorance is mother of arrogance “ despite Easter

RT @SABOURETCardio
Efficacy and Safety of #Alirocumab 300 mg Every 4 Weeks in Individuals With #T2D. Efficient and well tolerated 1/month. Associated with fixed #LLT combinations HI #statins and #ezetimibe #lipids https://academic.oup.com/jcem/article-abstract/104/11/5253/5510497

@teufel100 neeeee, so wars nicht gemaint. Ich mach zwar u.U. wenns hier ausfä#llt wirklich mein Internet übers Handy, aber meine Serverdienste sind alle "draußen".

RT @SABOURETCardio
Many expert panels and data support an #upfront strategy for #LLT in #ACS

RT @SABOURETCardio
#LLT “Do you speak #lipids ?” https://twitter.com/drpablocorral/status/1636764970020122624

Statin revisited.

❤️‍🔥 statin vs no-statin: 25% RRR MACE
❤️‍🔥 intense statin vs less intensive: addl 15% RRR
❤️‍🔥 high intensity statin w/⬇️50mg/dL achieved = 28% RRR MACE
3/ #llt

trying to understand why another provider told a young MI <55 yrs of age pt to stop their statin+eze and “just go with repatha, because it works better”.

Fourier and Odyssey were incremental add-on tx to baseline statin, ADDing RRR of 15%. https://link.springer.com/article/10.1007/s40119-020-00163-w #llt

RT @SABOURETCardio
Few events, p=0.047 but data which reinforce that very low #LDL after #ACS is safe and associated with further reduction of #MACE #LLT #PCSK9i https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehad144/7069638#.ZAop1Ho8TT8.twitter

#PAD - the forgotten #ASCVD component.

🦵🏾MI/CVA events higher in PAD than in prior MI/CVA pts!!!!
🦵🏾Low use of statins/other LLT in PAD 👀😮
🦵🏾#LLT effective in PAD: statinize!

#acc23

In an era of increased awareness surrounding #APOB, are we measuring this more and how does is relate to LDL-C?

@ldjande3 leading out on @Intermountain data. #acc23 #llt @KirkKnowlton

Fantastic work by my colleague, 2nd year internal medicine resident Dr Stephanie Skove - Complex Cases #CvPrev #LLT

Why we #acc23

present, discuss, learn

#clearoutcomes
🫀subgroups - yay benefit in women
🫀benefit seen in 1° 👀👍🏾 as well as 2°
🫀benefit in diabetes 🙌🏾🙌🏾

Important CVOT adding #BempedoicAcid into the hall of MACE reducing #LLT.
#acc23 #HeartPA #PhysicianAssociate

RT @SABOURETCardio
Important announcement of the webinar organised by ⁦@society_eas⁩ in good company with #WIC and other experts. Free registration #lipids #LLT #cardiotwitter

RT @SABOURETCardio
@drpablocorral @VietHeartPA Kind reminder before jumping to new #LLT : #BA and #Inclisiran aren’t on the French market. Maybe logical for an emerging country? 🤔

RT @SABOURETCardio
#LLT Post-discharge and long-term follow-up after an #ACS: International Collaborative Group of CNCF position paper. https://www.archivesofmedicalscience.com/Post-discharge-and-long-term-follow-up-after-an-acute-coronary-syndrome-International,150321,0,2.html#.Y_5bp3xwSvE.twitter

RT @SABOURETCardio
Open for discussion. New NICE guidelines #LLT #CVR #lipids https://www.nice.org.uk/guidance/gid-ng10178/documents/draft-guideline-2

A new #Labour Party group seems to have lots of money, but won't say where it comes from (very bad!). So does it have links to #EffectiveAltruism (even worse!)? Maybe if ‘Labour for the Long Term’ #LLT were more open, people wouldn't be so suspicious...
https://www.opendemocracy.net/en/labour-long-term-effective-altruism-wes-streeting/

Here, pt had a greater effect than anticipated (~45% reduction). Jumping to 80 mg (skipping 2 titrations) may only reduce an additional 18%.

Meanwhile, adding ezetimibe 10 mg could potentially drop LDL-C by 20% w/o risk of statin myalgia.

#LLT
https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehac709/6931821?redirectedFrom=fulltext&login=false