#lymphopenia as a major immunological abnormality that occurs in the majority (72%) of severe #COVID19 patients, can cause general immunosuppression facilitating viral persistence. Lymphopenia can be inherited or acquired. Acquired lymphopenia can be due to different biological conditions and disorders, however it is mainly related to #HIV and other viral infections.
#AIDS correlation with #SarsCoV2 N genotypes…
https://www.sciencedirect.com/science/article/pii/S2319417023000872#fig5

@novid

I wrote a long email afterwards, explaining how fucked up this is, how, though I shouldn’t be expected to defend my reasoning for not wanting to get #COVID, I take seizure medication that has the potential to cause #lymphopenia, which is part of the reason I needed to go get blood drawn.

My fit tested N95 respirator should NEVER have been removed without my consent. Especially given the fact that I had already declined to take it off for a temp check earlier in the appt!

#IDMastodon #Immunology #Clinicalreports #Clinicalstudy @jacionline. #Lymphopenia, particularly restricted to #Tcell compartment, has been described as one of the major clinical hallmarks in COVID-19 patients and proposed as a disease severity indicator. @Velardi_Lab et al demonstrate that the human thymus is a target of #SARSCoV2 & that thymic function is impaired in #COVID19 patients.
https://www.jacionline.org/article/S0091-6749(23)00147-1/pdf

2021
prolonged #SarsCov2 RNA virus shedding& #lymphopenia are hallmarks of #covid19 in #cancer #patients with poor prognosis

https://www.nature.com/articles/s41418-021-00817-9.epdf?sharing_token=5yexChNory8nWaxRPTu4M9RgN0jAjWel9jnR3ZoTv0OCy6qYvNYQ4ZbtZfR9eHLkJyGWIRr-STdnGyqW0QEnMrvv_T6_MxtCu4gIkJA8LQh_P8VFbq4Gqh8t_JC9QgZyhEHg_MVSCn_3cSnkOYUVxSbSQRBQVcKvsKPCqXtJpiA%3D

"In clinical studies, lymphocyte count has been described to recover to 80% of baseline value by 3 months; however, less is known about the duration of lymphopenia in real-life clinical practice."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641093/

#Immunology
#RepairingCovidDamage
#Covid19
#lymphopenia
#lymphocytes
#epidemiology
#virology

Weary. Verge of tears.