The ultra-rare #lysosomaldisease #MultipleSulfataseDeficiency (MSD) is a progressive currently incurable neurodegenerative disorder.
Here a #HighThroughput #DrugScreening allows identification of retinoids #tazarotene and #bexarotene as active therapeutic agents for MSD in-vitro.

By L. Schlotawa, J. Gärtner & colleagues at Uni Goettingen

🗞️ #openaccess: https://doi.org/10.15252/emmm.202114837