Gizmodo: An Existing Drug for Multiple Sclerosis Might Be Useful for Alzheimer's Too, Study Finds https://gizmodo.com/ms-ponesimod-might-be-useful-alzheimers-therapy-study-1850803952?utm_source=regular #insulindegradingenzyme #healthmedicalpharma #neuroinflammation #alzheimersdisease #amyloidplaques #amyloidosis #amyloidbeta #macrophages #glialcells #microglia #zhihuizhu #trem2
#insulindegradingenzyme #healthmedicalpharma #neuroinflammation #alzheimersdisease #amyloidplaques #amyloidosis #amyloidbeta #macrophages #glialcells #microglia #zhihuizhu #trem2
Fascinating to see #trainedimmunity used to condition immunomodulatory responses.
I guess it's about inducing the right #epigenetic programme, and then the functional effect can be anything.
#immunology #macrophages @JExpMed #tolerance #immunmodulation #science
https://rupress.org/jem/article/220/11/e20221388/276204/Trained-immunity-of-alveolar-macrophages-enhances?guestAccessKey=6d53512f-5c93-4720-8180-9180f44cda67&utm_source=NewJournalContent%27&%27utm_campaign%27=%27JEM%27&%27utm_medium%27=%27Email&nbd=28080031447&nbd_source=campaigner&_ccCt=g843-2q1v95-cqesgb-cwe4ixj4
#trainedimmunity #epigenetic #immunology #macrophages #Tolerance #immunmodulation #Science
Tissue-specific macrophages: how they develop and choreograph tissue biology
#immunology #macrophages #health #disease #science #medicine
https://www.nature.com/articles/s41577-023-00848-y?utm_source=nri_etoc&utm_medium=email&utm_campaign=toc_41577_23_9&utm_content=20230825
#immunology #macrophages #health #disease #Science #medicine
Research Associate - University of British Columbia
University of British Columbia
Come join our team at #UBC in beautiful #Vancouver as a Research Associate to study #TB, #pathogens, #macrophages, #immunity, and #drugdiscovery!!
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-british-columbia-27778-research-associate/?feed_id=55439
#ScienceJobs #hiring #research ...
https://jobrxiv.org/job/university-of-british-columbia-27778-research-associate/?feed_id=55439
#research #hiring #ScienceJobs #drugdiscovery #immunity #macrophages #pathogens #tb #vancouver #ubc
Researchers developed a sugar-bound #RNA drug that effectively targets #macrophages to fight #lungdamage. This innovation may be key to preventing severe #pneumonia, including cases like #COVID19: go.tum.de/749295
📷utah778 / iStock
#rna #macrophages #lungdamage #pneumonia #covid19 #medicalresearch #lunghealth
Oh inflammatory macrophages,
You swell and scar the heart's passages
Your unchecked activity
Leads to affliction, you see
But now there's a brighter outlook, alas
#afib #macrophages #inflammation #hearthealth #ode #poetry
Mechanisms driving immune cell recruitment during inflammation
#Neutrophils #Macrophages #inflammation #Science #Immunology #Scicomm
https://medicalxpress.com/news/2023-06-mechanisms-immune-cell-inflammation.html
#scicomm #immunology #science #inflammation #macrophages #Neutrophils
#Electron_tunneling associated with #ferritin in vivo in the #retina, the #cochlea, #macrophages and other tissues.
https://phys.org/news/2023-06-electron-tunneling-ferritin-vivo-retina-1.html
#electron_tunneling #ferritin #retina #cochlea #macrophages #mitochondria
Immune response to #TB infection determines disease outcomes. @RL_Kinsella @StallingsLab &co identify new roles for #autophagy in regulating proinflammatory responses of lung #macrophages to M. #tuberculosis infection #PLOSBiology https://plos.io/42GvBdn
#plosbiology #tuberculosis #macrophages #autophagy #TB
Stealthy #Salmonella escapes host's defenses using two-pronged approach
#immunity #vacuole #Xenophagy #macrophages
https://phys.org/news/2023-05-stealthy-salmonella-host-defenses-two-pronged.html
#Salmonella #immunity #vacuole #xenophagy #macrophages
How does #SARSCoV2 infect #macrophages?
A new @SciSignal study shows the virus enters both ACE2-expressing and -deficient macrophages, but replicates and triggers antiviral responses only in ACE2-expressing cells. https://scim.ag/2tl #press
@cyrilpedia Their observations show no change in the percentage of total #tumor associated #macrophages (TAMs) in the tumor tissue but a markedly increased percentage of NOS2+TAMs with no significant changes in arginase I expression...raising the question, which cell type would be the corresponding human counterpart? Macrophage or #monocyte ?
TREM2 and interstitial-like #macrophages orchestrate #airway #inflammation in #SARS-CoV-2 infection in rhesus #macaques https://www.nature.com/articles/s41467-023-37425-9
#macrophages #Airway #inflammation #sars #macaques
How Tattoos Interact With The Immune System Could Have Impacts for Vaccines https://hackaday.com/2023/04/05/how-tattoos-interact-with-the-immune-system-could-have-impacts-for-vaccines/ #CurrentEvents #MedicalHacks #immunesystem #macrophages #immunology #macrophage #Featured #Interest #Science #vaccine #immune #tattoo #ink
#CurrentEvents #MedicalHacks #immunesystem #macrophages #immunology #macrophage #Featured #Interest #Science #vaccine #immune #tattoo #ink
How Tattoos Interact With The Immune System Could Have Impacts for Vaccines - Tattoos are an interesting technology. They’re a way of marking patterns and desig... - https://hackaday.com/2023/04/05/how-tattoos-interact-with-the-immune-system-could-have-impacts-for-vaccines/ #currentevents #medicalhacks #immunesystem #macrophages #immunology #macrophage #featured #interest #science #vaccine #immune #tattoo #ink
#ink #tattoo #immune #vaccine #science #interest #featured #macrophage #immunology #macrophages #immunesystem #medicalhacks #currentevents
RT @Lo_Zanzi
Excited for our collaboration @naturemethods with @slavov_n: a new prioritized #SingleCell #MassSpec approach to increase proteome depth, reducing time, in our beloved #macrophages! We identified endocytic & proteolitic differences at the single cell lvl! http://doi.org/10.1038/s41592-023-01830-1
#singlecell #massspec #macrophages
Referenced link: https://phys.org/news/2023-03-macrophages-cancer-dye.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-03-macrophages-cancer-dye.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1640710881578196992#m
Labeling #macrophages associated with cancer progression using a selective dye @postech2020 @J_A_C_S https://pubs.acs.org/doi/10.1021/jacs.2c11393 https://phys.org/news/2023-03-macrophages-cancer-dye.html
#macrophages are an integral part of the solid tumor #microenvironment and have complex roles in #Immunology , #inflammation and #tissue homeostasis. Here is an elegant review on the topic of #innateimmunity in #cancer
https://www.cell.com/cell/fulltext/S0092-8674(23)00163-0
#macrophages #microenvironment #immunology #inflammation #tissue #innateimmunity #cancer
Referenced link: https://medicalxpress.com/news/2023-03-immune-neighborhoods-highlights-macrophages-key.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-immune-neighborhoods-highlights-macrophages-key.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1636396939921981442#m
RT by @physorg_com: Study of immune 'neighborhoods' highlights #macrophages as key players in invasive breast cancers @naturecancer https://medicalxpress.com/news/2023-03-immune-neighborhoods-highlights-macrophages-key.html
RT @lab_mass
#macrophages are true all-rounders! 😍We just don't know all of it....yet! https://rdcu.be/c7HqX Check out our review on macrophage development and how they choreograph tissue biology! @FNimmerjahn @KierdorfLab @LabSchlitzer https://twitter.com/NatRevImmunol/status/1636072405927100417