In 2020, after multiple visits to doctors and specialists, we found out that my dad's failing eyesight was due to macular degeneration (which he still calls immaculate degeneration sometimes).

He gave up his driver's license officially at that point (though he unofficially gave up driving before then and I shuttle him around to where he needs to go).

Then he hurt his back. He has two crushed vertebrae and it causes him no end of grief. He can't really stand up straight and he can't walk for too long.

We (my parents, my husband, and I) talked it out and decided they should move in to town (pop. 3000), where we live. The blue house is about 15 minutes out of town, in a community of about 250.

With neither of my parents having a license anymore, moving them to town meant they could get groceries and prescriptions delivered and didn't have to rely on me for everything. They'd get more independence.

#aging #parents #maculardegeneration

Antidepressant Drug May Prevent Blindness; Best Of: Oct, 2021
Those taking the antidepressant drug fluoxetine, branded as Prozac, have a significantly reduced risk of developing progressive age-related macular degeneration.#amd #maculardegeneration #blindness #fluoxetine #prozac
https://youtu.be/xTA1eN_-cyI

Coverage of Luxa Biotechnology & NSCI's clinical trial update in the @EmmesCRO session at #ARVO2023 by Ophthalmology Times:
https://zurl.co/QRR2
@OphthTimes
#maculardegeneration #stemcell #clinicaltrial

Happening today at #ARVO2023! Jeffrey Stern joins a distinguished panel to discuss Ophthalmic Cell & Gene Therapies hosted by @EmmesCRO.

Jeff co-founded both RRF & Luxa Biotech., sponsor of our Phase 1/2a clinical trial for a #StemCellTherapy to treat #maculardegeneration.

This broad review covers cell products being developed to replace brain & retinal cells that are lost due to conditions like #Alzheimers disease, #Parkinsons disease and age-related #maculardegeneration, and some remaining hurdles to bring these reparative therapies to patients.

We are excited for #ARVO2023! NSCI investigator Nathan Boles will present data on retinal pigment epithelium subpopulations identified by #scRNAseq and director of translational programs Jeff Stern will share insights from our Phase1/2a clinical trial for #maculardegeneration.

Referenced link: https://medicalxpress.com/news/2023-03-antibody-based-drug-triggers-rare-inflammatory.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-antibody-based-drug-triggers-rare-inflammatory.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1641797502331486208#m

RT by @physorg_com: An antibody-based drug triggers rare inflammatory eye problems in #maculardegeneration patients @sciencetm https://www.science.org/doi/10.1126/scitranslmed.abq5241 https://medicalxpress.com/news/2023-03-antibody-based-drug-triggers-rare-inflammatory.html

With retinal pigment epithelium (RPE) cell replacement therapies entering clinical trials, including our Phase 1/2a trial with allogeneic adult RPE, the field of #MacularDegeneration research is breaking new ground that can provide insights for other ocular #stemcell therapies.

RT @BPoD_mrc
Sight Mapping – Genetic risk factors for age-related #maculardegeneration #armd Image & research by Mazal Cohen-Gulkar, Ahuvit David & Naama Messika-Gold et al @asherypadan1 lab @TelAvivUni in @PLOSBiology. Read more on http://bpod.mrc.ac.uk/archive/2023/3/10 with @MRC_LMS and @AntDLewis

We're making bank(s of human pluripotent #stemcell lines)! #NeuraCell distributes hPSCs & hPSC-derived cell types, including neural progenitor cells & retinal pigment epithelium, made from #tauopathy and #maculardegeneration patient lines.

Request yours: https://www.neuracell.org/cell-supply

We ❤️ #stemcells for modeling #neurodevelopment, #Alzheimers, #MacularDegeneration and more.

#NeuraCell

RT @RetinaGlobal1
This research has been published in @PLOSBiology.

#ophthalmology #retina #MacularDegeneration #AgeRelated

http://bit.ly/3ltxZEE

The Univ. of Michigan Kellogg Eye Center 2022 annual report has been released, including features on Sally Temple's election to NAM & our Phase 1/2a trial for stem cell treatment of #maculardegeneration led by Dr. Rajesh Rao. @UMKelloggEye @surgeonretina
https://issuu.com/u-mkelloggeyecenter/docs/annual_report_online_version

Real-World Data Shown to Match Eye Disease Trial Results

#Research findings show data in patients' electronic #health records can be collected and analyzed to replicate results from late-stage clinical trials of an #eye disease #biologic drug.

https://sciencebusiness.technewslit.com/?p=44351

#News #Science #Business #MacularDegeneration #WetAMD #ClinicalTrials #RealWorldEvidence #Algorithms #Analytics #PatientRegistry #Ophthalmology #ElectronicHealthRecords

Causes of #blindness: LHX2 & OTX2 regulate the #retinal pigmented epithelium differentiation program; a causal risk SNP contributes to age-related #MacularDegeneration by altering binding of LHX2-OTX2 to TRPM1 promoter @asherypadan1 &co #AMD #PLOSBiology https://plos.io/3HcLvok

Causes of #blindness: LHX2 & OTX2 regulate the #retinal pigmented epithelium differentiation program; a causal risk SNP contributes to age-related #MacularDegeneration by altering binding of LHX2-OTX2 to TRPM1 promoter @asherypadan1 &co #AMD #PLOSBiology https://plos.io/3HcLvok

Causes of #blindness: LHX2 & OTX2 regulate the #retinal pigmented epithelium differentiation program; a causal risk SNP contributes to age-related #MacularDegeneration by altering binding of LHX2-OTX2 to TRPM1 promoter @asherypadan1 &co #AMD #PLOSBiology https://plos.io/3HcLvok

“After they confirmed the presence of synaptic connections, the researchers analyzed the cells involved and found that the most common retinal cell types forming synapses were photoreceptors – rods and cones – which are lost in diseases like #retinitispigmentosa and age-related #maculardegeneration, as well as in certain eye injuries. The next most common cell type, retinal ganglion cells, are degenerate in optic nerve disorders like #glaucoma.

“That was an important revelation for us,” says Gamm. “It really shows the potentially broad impact these retinal organoids could have.””

Age-Related #MacularDegeneration a #Risk Factor for #COVID-19 #Infection and Severe #Disease.

https://neurosciencenews.com/amd-covid-22161/

Get ready for some next level eye care technology – introducing the Arges glasses by Cellico. These high-tech specs relocate unseen images for clearer vision – it's mesmerizing!

Built into the bridge of the eyewear is a small 4K camera. Live video from the camera is visible on a screen to one side of the user's field of vision – where they're actually able to see it – via a display on the inside of the glasses' lenses.

#EyeCare #TechForGood #MacularDegeneration

https://newatlas.com/wearables/arges-glasses-macular-degeneration/