Another LAICPMS day, another totally new (to us!) problem. This supports my hypothesis that LAICPMS NEVER goes smoothly. No one cried though, so it could have been worse!

#ECR #LAICPMS #MassSpectrometry #geochemistry

Happy to announce that we've just put up our preprint for the #OpenMS 3.0 release:

https://www.researchsquare.com/article/rs-3286368/v1

OpenMS is the by far the largest software project that I've ever worked on, and this is the first major release during my tenure here. Happy to answer any questions.

#TeamMassSpec #FOSS #OpenScience #OpenSource #Proteomics #massSpectrometry

RT @Matrix_Science: You don't need a fancy new search engine to identify peptides from chimeric spectra. Just process the raw file in Mascot Distiller and search with Mascot Server. #proteomics #MassSpec #MassSpectrometry #Bioinformatics

https://www.matrixscience.com/blog/identifying-peptides-from-chimeric-spectra-dda-dia.html

Lab days are an exercise in zen. Nothing like watching all the careful organisation go out the window. Of course, not preparing isn't an option either.

#LAICPMS #MassSpectrometry #ECRchat

Vlad the Impaler may have shed tears of blood, study finds - Enlarge / This 1475 letter written by Vlad the Impaler contains protein... - https://arstechnica.com/?p=1961945 #massspectrometry #paleoproteomics #vladtheimpaler #archaeology #proteomics #chemistry #science #biology #dracula

What tool do you use to collect metadata for #massspectrometry experiments? I want to overhaul our current system to be more flexible and exhaustif. I started to record things in a spreadsheet using SDRF but it is a bit tedious and the format itself doesn't respect tabular data good practices. #teammassspec #bioinformatics

#TeamMassSpec #Proteomics #MassSpectrometry: Have you used or hear of #OpenMS? Would you be interested in filling out a survey to guide our future development? Please go to: https://www.surveymonkey.de/r/9F6TMJL
You will get my gratitude, and, for a limited time, if you toot me that you filled it out a free random fact of my choosing. Come help support #OpenScience #FOSS #OpenSource

Just in case anyone in #TeamMassSpec is curious, the likely culprit of my 248.9 m/z ion from this thread: https://mstdn.science/@sarahehancock/110818463525422168 is free cyanide reacting with the gold seals of the HPLC pump. I will have to try a few different brands of solvent to see if I can ameliorate this issue. More info also available here: https://community.agilent.com/technical/lcms/f/forum/5480/how-do-we-get-rid-of-identify-contamination-with-m-z-248-9737-negative-mode.

#metabolomics #lipidomics #massspectrometry #massspec

RT @: Interested in participating in the @MyABRF iPRG-2023 Proteome Informatics Research Group Study on #Crosslinking #MassSpectrometry Data Analysis? Fill in Google Survey using the link below:

Hey #TeamMassSpec, I'm having issues with a contaminant ion @ 248.9 m/z in -ve ion mode when running 90% ACN 10 mM AmOAc at pH 9. Found a thread on research gate suggesting it comes from the ACN but have tried two brands now with no joy. Has anyone else had this problem?

Research gate link: https://researchgate.net/post/What-is-this-contaminant-with-m-z-2489718

ACN brands tried: Fisher Sci Optima, Supelco LiChroSolv. LiChroSolv has a lot less of it than Fisher Sci.

#metabolomics #lipidomics #massspectrometry #massspec

A new technique can reveal the unknown molecules in nature. The technique combines mass spectrometry, a method that measures the mass and charge of molecules, with machine learning, a branch of artificial intelligence that learns from data. The technique can help discover new natural products, such as drugs, pesticides, and fragrances.

#MassSpectrometry #MachineLearning #NaturalProducts https://phys.org/news/2023-06-mass-spectrometry-combo-nature-unknown.html?utm_source=flipboard&utm_content=HariTulsidas%2Fmagazine%2FMind+and+Matter

On my way back home from Uzhhorod, Ukraine 🇺🇦 after an intense week teaching #rstats, #datascience, #massspectrometry and #proteomics to young Ukrainians students and researchers at Biological Data Science Summer School.

https://www.bds3.org/

The whole faculty team is unequivocal: the participants are bright, talented, hardworking, with a passion to learn and understand.

Can someone who knows something about mass spectrometry explain why the Agilent 8900 is called a triple quadrupole, when I'm fairly sure there are only two quads??

#labWork #MassSpectrometry #MassSpec

Apparently someone has been gently persuading the mass spec this morning 🔨 not convinced that's a recommended approach 😅

#LabWork #MassSpectrometry #HammerTime

RT @: Great collection of relevant publications: Machine Learning in Proteomics and Metabolomics https://pubs.acs.org/doi/full/10.1021/acs.jproteome.2c00566?ref=vi_machine-learning-omics&utm_content=bufferd7719&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer #MachineLearing #Massspectrometry #ArtificialIntelligence #Proteomics #Metabolomics #PrecisionMedicine #Biology #Biomarkers #Multiomics #Datasciences

Beer byproducts were popular canvas primers for Danish Golden Age artists - Enlarge / Two Russian Ships of the Line Saluting by Christoffer Wilhelm... - https://arstechnica.com/?p=1941236 #massspectrometry #artconservation #danishgoldenage #heritagescience #proteomics #culture #science #physics #beer #art

RT @GitinKatie: There it is!! Introducing the new #IntabioZT. Stop by the @SCIEXnews Hospitality Suite tonight at 8 PM in the Hilton to see it in person @asmsnews

#SciexTAP #icief #MassSpectrometry #ASMS2023

@wfondrie kicks off the second edition of our #MachineLearning for #MassSpectrometry short course at #ASMS2023 for a full room.

Sunrise over the George R. Brown convention center in Houston, TX. Ready for six days of hardcore #MassSpectrometry science! #ASMS2023

A beleaguered Mars rover could’ve ended up in a museum when the Ukraine war suspended launch AGAIN, but new funds are keeping it alive. Read my first for @KnowableMag and learn about the instrument aboard--the mass spectrometer--that’s the linchpin of a strategy to find signs of life on Mars. https://knowablemagazine.org/article/physical-world/2023/mission-could-transform-understanding-mars

#EUSpace
#Space
#Aerospace
#ESA
#NASA
#ExoMars
#Mars
#Science
#MassSpectrometry
#AnalyticalChemistry
#Chemistry