Molecular #mechanisms of #SARS-CoV-2 #resistance to #nirmatrelvir, Nature: https://www.nature.com/articles/s41586-023-06609-0 #research #antivirals #covid19 #drugs #mutations #mpro #protease
#mechanisms #sars #resistance #nirmatrelvir #research #antivirals #COVID19 #drugs #mutations #mpro #protease
The King is Dead! Influence vs. control in tabletop games.
Skeleton Code Machine: https://www.skeletoncodemachine.com/p/manipulating-a-kingdom-divided
.
#boardgames #ttrpg #rpg #rpgdesign #boardgamedesign #thekingisdead #influence #control #mechanics #mechanisms #paxrenaissance #paxren
#boardgames #ttrpg #rpg #rpgdesign #boardgamedesign #thekingisdead #influence #control #mechanics #mechanisms #paxrenaissance #paxren
With the usual #statistician’s caveat that #causality is really hard to sort out in data like this even with good #controls … yes, I believe this. And the #mechanisms aren’t hard to find, either. π
#causality #statistician #controls #mechanisms
Chemical engineer by training and profession. Spent my last working decade in the network and transport layers, plus security architecture. Retired now.
Never used the bird, ran from the faceplant and tightly constrain other social. Watched #Explore here for a bit and found interesting and welcoming positivity. Hoping to find a community to exchange and discuss ideas.
Fan of science fiction and original research in mammalian biology, microbiology and systems/network biology.
#biology #microbiology #systemsbiology #networkmedicine #ecoevo #pleiotropy #mechanisms #hiking #olympicweightlifting
#introduction #explore #biology #microbiology #systemsbiology #NetworkMedicine #ecoevo #pleiotropy #mechanisms #hiking #olympicweightlifting
It's Skeleton Code Machine day!
This week we look at three interesting tabletop mechanisms from Obsession! Reputation systems, workers as a resource, and penalties for unused purchases.
Put on your fancy hat, check your reputation, and meet me in the front parlour.
Obsession! π§π©
https://www.skeletoncodemachine.com/p/obsession
#boardgames #ttrpg #boardgamedesign #rpgdesign #rpg #ttrpg #python #mechanics #mechanisms #tabletop #gamedesign
#boardgames #ttrpg #boardgamedesign #rpgdesign #rpg #python #mechanics #mechanisms #tabletop #gamedesign
In December 2022, #Montreal hosted the 15th Conference of the Parties (#COP15 ) to the #UnitedNations Convention on #BiologicalDiversityΒ (CBD).Β
This article #summarizes #mechanisms in #support of COP15 #commitments from a #Canadian perspective, and the means by which #Canada can #fulfill these commitments with #respect , notably to #Indigenous and #environmental #law .
https://www.lexology.com/library/detail.aspx?g=7acc98e3-9045-4a79-9504-e44cca941a40
#montreal #COP15 #unitednations #biologicaldiversity #summarizes #mechanisms #support #commitments #canadian #canada #fulfill #respect #indigenous #environmental #law #climatechange #climateaction #stopecocide #degrowth
Matej Kohar just published Neural Machines: A Defense of Non-Representationalism in Cognitive Neuroscience, where he argues that mechanistic explanation is incompatible with representations. I think they can be made compatible (cf. my "Situated Neural Representations: Solving the Problems of Content" in Fronties in Neurorobotics), but any representationalists who are also mechanists will need to think of something to say about this.
RT @AbioticStress
Review by Busoms et al. @UABBarcelona @MPlantPCom @CellPressNews
Chasing the #Mechanisms of #Ecologically Adaptive #Salinity Tolerance
https://www.cell.com/plant-communications/fulltext/S2590-3462(23)00069-X#%20
#PlantSci #AgTwitter #Abiotic @ESA_org @BritishEcolSoc @EUAgri @SciSustAg @NAP_Africa @BinfoTrends @ciwf @CGIAR_EiB
#mechanisms #ecologically #salinity #plantsci #agtwitter #abiotic
Hey San Diego!
If you are not at #SLAS23 next week to visit our booth, you definitely should not miss Mike Hildebrand's amazing talk about investigating novel #mechanisms of #pain at the #translationalresearch conference using @3Brain's #biointerface technology.
#slas23 #mechanisms #pain #translationalresearch #biointerface
New game mechanism video: Neighbour Scope, in which players can interact with their immediate neighbours. -A
Why do people (not) give?
Some thoughts on #motivation, #justification, and #mechanisms that drive #engagement in #nonprofits, #philanthropy
https://renebekkers.wordpress.com/2023/01/30/why-do-people-not-give/
#motivation #justification #mechanisms #engagement #nonprofits #philanthropy
I want to live in a world where #advertising doesn't #exist.
#Capitalism brought us to the max pinnacle of #tech #progress, where it could take us, but now we have begun to move downward, because the same #mechanisms that stimulated #development are now in the hands of those who have #money.
->
#advertising #exist #capitalism #tech #progress #mechanisms #development #money
It is possible that there are specialized binding or #transport #mechanisms in MV membranes for PPi generated locally by NTPPPH activity.
Further research is needed to investigate this mechanism.
The role of the family in health promotion: a scoping review of models and mechanisms (240 studies)
https://pubmed.ncbi.nlm.nih.gov/36398941/
Ecological systems #theory, social cognitive theory, family systems theory and the theory of planned behaviour most widely used in explaining #context and/or #mechanisms. Family support, supervision and modelling most common.
#healthpromotion #behaviourchange #publichealth #behaviorchange #psychology #theory
#theory #context #mechanisms #healthpromotion #BehaviourChange #publichealth #BehaviorChange #psychology
#introduction I am a research scientist at the #BroadInstitute in #Cambridge with an interest in #Ubiquitin #ligase #structuralbiology and #mechanisms. Here for the #science toots about #biotech #DrugDiscovery #ChemicalBiology #TPD #targetedproteindegradation #biophysics #biochemistry #HDX #NMR #SAXS #CryoEM
#introduction #broadinstitute #Cambridge #Ubiquitin #ligase #structuralbiology #mechanisms #Science #biotech #DrugDiscovery #ChemicalBiology #TPD #targetedproteindegradation #biophysics #biochemistry #HDX #NMR #SAXS #cryoem
Nice to meet you on Mastodon.ca! βπ¨π¦ βIntro:Ph.D. (Yale '87); research in #Genomics, #Cytogenetics, #Bioinformatics, #Humangenetics. Established biotech co, #Cytognomix (2009; https://www.cytognomix.com). Produce #Software to estimate #Radiation exposure (#Biodosimetry), #Chemotherapy response, interpreting #Gene #Variants, #RNA #Mechanisms, #Geostatistics #Epidemiology of COVID19. Also #Professor emeritus, adjunct in #Biochemistry & #Oncology #WesternUniversity @PeterKRogan, progan@uwo.ca
#genomics #cytogenetics #bioinformatics #humangenetics #cytognomix #software #radiation #chemotherapy #gene #variants #RNA #mechanisms #epidemiology #biodosimetry #Professor #biochemistry #oncology #geostatistics #westernuniversity
How petrol pumps know when to turn themselves off
https://www.youtube.com/watch?v=fT2KhJ8W-Kg
Some of these everyday things in our life are #designed in extremely clever ways that simply #learning how it works can blow your mind. This #video is an example of that, and it #explains all of the #mechanisms involved in such a simple and intuitive way that anyone could understand it. Definitely one of the best #explainer #videos I've seen.
#YoutubeVids #Educational #SteveMould #HowItWorks #PetrolPumps #Engineering
#designed #learning #video #explains #mechanisms #explainer #videos #youtubevids #educational #steveMould #howitworks #Petrolpumps #engineering
How petrol pumps know when to turn themselves off
https://www.youtube.com/watch?v=fT2KhJ8W-Kg
Some of these everyday things in our life are #designed in extremely clever ways that simply #learning how it works can blow your mind. This #video is an example of that, and it #explains all of the #mechanisms involved in such a simple and intuitive way that anyone could understand it. Definitely one of the best #explainer #videos I've seen.
#YoutubeVids #Educational #SteveMould #HowItWorks #PetrolPumps #Engineering
#designed #learning #video #explains #mechanisms #explainer #videos #youtubevids #educational #steveMould #howitworks #Petrolpumps #engineering
How petrol pumps know when to turn themselves off
https://www.youtube.com/watch?v=fT2KhJ8W-Kg
Some of these everyday things in our life are #designed in extremely clever ways that simply #learning how it works can blow your mind. This #video is an example of that, and it #explains all of the #mechanisms involved in such a simple and intuitive way that anyone could understand it. Definitely one of the best #explainer #videos I've seen.
#YoutubeVids #Educational #SteveMould #HowItWorks #PetrolPumps #Engineering
#designed #learning #video #explains #mechanisms #explainer #videos #youtubevids #educational #steveMould #howitworks #Petrolpumps #engineering