📰 "Microstructure-Based Modeling of Primary Cilia Mechanics"
by 🔬 Nima Mostafazadeh, Andrew Resnick, Y-N Young, Zhangli Peng
https://pubmed.ncbi.nlm.nih.gov/37503231/ #Mechanosensing #Microtubule #Mechanics

📰 "Two-dimensional molecular condensation in cell signaling and mechanosensing"
by 🔬 Xiangfu Guo, Kexin Zhu, Xinlu Zhu, Wenting Zhao, Yansong Miao
https://pubmed.ncbi.nlm.nih.gov/37475548/ #Mechanosensing #Mechanical #Cell

📰 "Cell-strain-energy costs of active control of contractility"
by 🔬 Josephine Solowiej-Wedderburn, Carina M Dunlop
https://pubmed.ncbi.nlm.nih.gov/37464714/ #Mechanosensing #Cell

📰 "Allosteric activation of vinculin by talin"
by 🔬 Florian Franz, Rafael Tapia-Rojo, Sabina Winograd-Katz, Rajaa Boujemaa-Paterski, Wenhong Li, Tamar Unger, Shira Albeck, Camilo Aponte-Santamaria, Sergi Garcia-Manyes, Ohad Medalia, Benjamin Geiger et al.
https://pubmed.ncbi.nlm.nih.gov/37463895/ #Mechanosensing #Actin

📰 "Extracellular matrix sensing via modulation of orientational order of integrins and F-actin in focal adhesions"
by 🔬 Valeriia Grudtsyna, Swathi Packirisamy, Tamara C Bidone, Vinay Swaminathan
https://pubmed.ncbi.nlm.nih.gov/37463754/ #Mechanosensing #Actin #Cell

📰 "Microstructure-Based Modeling of Primary Cilia Mechanics"
by 🔬 Mostafazadeh, N., Resnick, A., Young, Y.-N., Peng, Z.
http://biorxiv.org/content/10.1101/2023.07.14.549117v1?rss=1 #Mechanosensing #Microtubule #Mechanics

📰 "Cofilin-Driven Nuclear Deformation Drives Dendritic Cell Migration through the Extracellular Matrix"
by 🔬 Warner, H., Franciosa, G., van der Borg, G., Faas, F., Koenig, C., de Boer, R., Classens, R., Maassen, S., Baranov, M., Mahajan, S., Dabral, D. D., Coenen, B., Bianchi, F., van Hilten et al.
http://biorxiv.org/content/10.1101/2023.07.10.548429v1?rss=1 #Mechanosensing #CellMigration #Cell

📰 "Studying structure and functions of cell membranes by single molecule biophysical techniques"
by 🔬 Qingrong Zhang, Siying Li, Yu Yang, Yuping Shan, Hongda Wang
https://pubmed.ncbi.nlm.nih.gov/37288104/ #Mechanosensing #Cell

📰 "Retinoic acid receptor β modulates mechanosensing and invasion in pancreatic cancer cells via myosin light chain 2"
by 🔬 Carlos Matellan, Dariusz Lachowski, Ernesto Cortes, Kai Ning Chiam, Aleksandar Krstic, Stephen D Thorpe, Armando E Del Río Hernández
https://pubmed.ncbi.nlm.nih.gov/37130839/ #Mechanosensing #Mechanical #Myosin

📰 "A luciferase fragment complementation assay to detect focal adhesion kinase (FAK) signaling events"
by 🔬 Jason A Estep, Lu O Sun, Martin M Riccomagno
https://pubmed.ncbi.nlm.nih.gov/37089315/ #Mechanosensing #Adhesion

📰 "Actin Bundles Dynamics and Architecture"
by 🔬 Sudeepa Rajan, Dmitri S Kudryashov, Emil Reisler
https://pubmed.ncbi.nlm.nih.gov/36979385/ #Mechanosensing #Dynamics #Actin

News from Till:

Delighted to announce a new #EPSRC project on #microfluidics to study #mechanosensing. With #WarwickUni colleagues Michael Smutny and Sascha Ott, Melikhan Tanyeri from Duquesne University, and 3i as project partner:

https://gow.epsrc.ukri.org/NGBOViewGrant.aspx?GrantRef=EP/X026663/1

📰 "Multiscale Computational Framework to Investigate Integrin Mechanosensing and Cell Adhesion"
by 🔬 Montes, A. R., Gutierrez, G., Buganza Tepole, A., Mofrad, M.
http://biorxiv.org/content/10.1101/2023.03.24.533575v1?rss=1 #Mechanosensing #Cell

📰 "Systematic analysis of RhoGEF/GAP localizations uncovers regulators of mechanosensing and junction formation during epithelial cell division"
by 🔬 Florencia di Pietro, Mariana Osswald, José M De Las Heras, Inês Cristo, Jesús López-Gay, Zhimin Wang, Stéphane Pelletier, Isabelle Gaugué, Adrien Leroy, Charlotte Martin, Eurico Morais-de-Sá et al.
https://pubmed.ncbi.nlm.nih.gov/36917931/ #Mechanosensing #CellDivision #Cell

📰 "Specialized actin nanoscale layers control focal adhesion turnover"
by 🔬 Kumari, R., Ven, K., Chastney, M., Peranen, J., Arron, J., Almeida-Souza, L., Kremneva, E., Poincloux, R., Chew, T. L., Gunning, P. W., Ivaska, J., Lappalainen, P.
http://biorxiv.org/content/10.1101/2023.02.15.528622v1?rss=1 #Mechanosensing #Actin #Cell

A fly library of fluorescently labeled RhoGEF/GAP to unveil molecular mechanisms of de novo junction formation and neighbor response upon cell division.
#Drosophila #development #biology #CellDivision #MechanoBiology #MechanoSensing
https://www.cell.com/current-biology/fulltext/S0960-9822(23)00062-3

📰 "Phosphoproteomics of cellular mechanosensing reveals NFATC4 as a regulator of myofibroblast activity"
by 🔬 Mattner, L. F., Zeng, Z., Mayr, C. H., Ansari, M., Wei, X., Asgharpour, S., Kneidinger, N., Stoleriu, G. M., Behr, J., Polleux, J., Yildirim, A. O., Burgstaller, G., Mann, M., Schiller et al.
http://biorxiv.org/content/10.1101/2023.02.13.528335v1?rss=1 #Mechanosensing #Cell

📰 "Multi-scale Modelling of Shear Stress on the Syncytiotrophoblast: Could Maternal Blood Flow Impact Placental Function Across Gestation?"
by 🔬 Tet Chuan Lee, Ali Moulvi, Joanna L James, Alys R Clark
https://pubmed.ncbi.nlm.nih.gov/36745293/ #Mechanosensing #Cell

📰 "Targeting sterol regulatory element binding proteins (SREBPs) activation lowers intraocular pressure by halting its mechanosensing function in the trabecular meshwork"
by 🔬 Wang, T., Soundararajan, A., Rabinowitz, J., Jaiswal, A., Osborne, T., Pattabiraman, P. P.
http://biorxiv.org/content/10.1101/2023.02.05.527136v1?rss=1 #Mechanosensing #Actin

📰 "Bacterial mechanosensing of surface stiffness promotes signaling and growth leading to biofilm formation by Pseudomonas aeruginosa"
by 🔬 Wang, L., Wong, Y.-C., Correira, J., Wancura, M., Geiger, C., Webster, S. S., Butler, B., O'Toole, G. A., Langford, R., Brown, K., Dortdivanlioglu, B., Webb, L., Cosgriff-Hernandez, E., Gordon, V.
http://biorxiv.org/content/10.1101/2023.01.26.525810v1?rss=1 #Mechanosensing #Mechanical #Adhesion