The EMBO Journal · @embojournal
552 followers · 286 posts · Server sciencemastodon.com

A mitochondrial /#PHD2--alpha axis drives progression by enhancing metabolic adaptation to stress

-induced EglN1- interaction on safeguards AMPKα activation and homeostasis during breast cancer growth

embopress.org/doi/full/10.1525

#egln1 #ampk #breastcancer #hypoxic #Hypoxia #camkk2 #mitochondrial #metabolic

Last updated 1 year ago

American Naturalist · @ASNAmNat
1966 followers · 184 posts · Server ecoevo.social

Can acquisitions ever become permanent? Here, Alexandra Brown, Grace Casarez, and @mixotrophe apply to a model of "" to find out when borrowed machinery is better than having your own.
Read now ahead of print! journals.uchicago.edu/doi/10.1

#metabolic #AdaptiveDynamics #chloroplaststealing #microbes

Last updated 1 year ago

CellBioNews · @cellbionews
69 followers · 1531 posts · Server scientificnetwork.de
CircadianHealth · @CircadianHealth
56 followers · 140 posts · Server med-mastodon.com

• Inadequate is associated with an increased risk of disorders.
• Mitochondrial metabolism lies at the heart of a homeostatic sleep-regulatory mechanism.
• Sleep need is encoded in the excitability state of sleep-control neurons in the central fly brain.
ROS promotes sleep by acting on a redox-sensitive potassium channel subunit.
• Mitochondrial ROS modulates the activity of sleep-control
sciencedirect.com/science/arti

#sleep #metabolic #mitochondrial #neurons

Last updated 1 year ago

Poetry News · @haikubot
767 followers · 8059 posts · Server mastodon.cloud

Metabolic associated fatty liver's on the rise
Though in genetics, obesity's the surprise
It's not just these two playing the game
For diet and lifestyle share the blame
What was once uncommon is now the norm
The earlier we take action, the better the form

medicalnewstoday.com/articles/

#metabolic #fattyliver #obesity #lifestyle #health #prevention #poetry

Last updated 1 year ago

Soheb · @soheb
42 followers · 1132 posts · Server pkutalk.com

If you haven't heard, @poconnor is donating half of her profits from "Living with PKU" to the NSPKU - a fantastic charity that helps people with the rare disorder called PKU!

And if you buy both of her books, you get 25% off!

Get her books here now:

pigpen.page/books/

Also, please boost! Boosts are incredibly welcome!!

#phenyketonuria #phenylcetonurie #phenylalanine #book #books #bookstodon #pku #metabolic #metabolicdiet #metabolicdisease

Last updated 1 year ago

Soheb · @soheb
42 followers · 1131 posts · Server pkutalk.com

Just noticed @poconnor has made a new blog - and it contains her utterly fantastic new graphic that explains how PKU is passed on from parents!

Give it a read here on her blog:

pigpen.page/the-genetics-of-pk

#pigpen #phenyketonuria #pku #phenylalnine #genetics #health #metabolic #metabolicdiet #metabolicdisease #dna #sapropterin

Last updated 1 year ago

The EMBO Journal · @embojournal
451 followers · 195 posts · Server sciencemastodon.com

How can & cues modulate the response? María Moriel-Carretero et al find master kinase /ATM to bind at the , altering its availability in the nucleus and impacting kinetics, intensity and persistence of DNA DSB responses in yeast and human cells

c/o @ReviewCommons

embopress.org/doi/10.15252/emb

#metabolic #environmental #dnadamage #tel1 #pi4p #golgi #refereedpreprint

Last updated 1 year ago

Soheb · @soheb
40 followers · 1005 posts · Server pkutalk.com

A question to the PKU community:

What would you say to parents who have just discovered that their child has PKU?

#pku #phenylketonuria #parenting #parents #lowprotein #metabolic #phenylcetonurie #phenylalanine

Last updated 1 year ago

Soheb · @soheb
37 followers · 969 posts · Server pkutalk.com

Me as a child whenever I had to drink Maximaid in public

#pku #phenylketonuria #lowprotein #metabolicdiet #metabolic

Last updated 1 year ago

CircadianHealth · @CircadianHealth
55 followers · 138 posts · Server med-mastodon.com

Our findings establish a pivotal role of clock in dictating liver rhythmicity and diurnal , and suggest targeting intestinal rhythms as a new avenue for improving health.
sciencedirect.com/science/arti

#intestine #metabolism #metabolic

Last updated 1 year ago

ConscienHealth · @ConscienHealth
43 followers · 233 posts · Server med-mastodon.com

First it was or weight loss . Then it became and bariatric surgery. Maybe it's time to drop the confusing "bariatric" label. Because metabolic surgery has an enduring role to play in .
conscienhealth.org/2023/05/goo

#bariatric #surgery #metabolic #obesitycare

Last updated 1 year ago

JIPB · @JIPB
38 followers · 136 posts · Server mstdn.science

Sun et al. provide a comprehensive perspective of the landscape during , shedding light on the and mechanisms of formation.
doi.org/10.1111/jipb.13495.
@wileyplantsci

#cellular #soybean #nodulation #metabolic #developmental #nodule #JIPB #plantscience #nitrogenfixation

Last updated 2 years ago

CellBioNews · @cellbionews
43 followers · 959 posts · Server scientificnetwork.de
Sean Gibbons · @gibbological
209 followers · 412 posts · Server mstdn.science

RT @NatureMedicine
Integrated analyses reveal that multiomics captured the heterogeneity of states accompanying and changes in metabolic health in response to intervention which are not apparent in measurements. @nrappapo @isbsci
nature.com/articles/s41591-023

#metabolic #obesity #lifestyle #bmi

Last updated 2 years ago

CellBioNews · @cellbionews
37 followers · 836 posts · Server scientificnetwork.de
The EMBO Journal · @embojournal
424 followers · 128 posts · Server sciencemastodon.com

Highlighted in issue 6: balancing growth and defense in

Reviews on HIF regulation of crosstalk in tumor , and origins of responses

Further:
Phase separation of signalling complexes
oxidative stress checkpoint via DNA-PKcs and ATM

Cover by @tatsuofukagawa1 and colleagues

embopress.org/toc/14602075/202

#phytosulfokine #plants #metabolic #microenvironment #evolutionary #auxin #hippo #mitochondrial

Last updated 2 years ago

Open Book Publishers · @OpenBookPublish
228 followers · 13 posts · Server hcommons.social

📢Out Now in OA: 'Introduction to : for Flipped-classroom Teaching' by Thomas Sauter and Marco Albrecht.

This book is an introduction to the language of systems biology, which is spoken among many disciplines, from biology to .

Authors Thomas Sauter and Marco Albrecht draw on a multidisciplinary background and evidence-based learning to facilitate the understanding of networks, modeling and system dynamics.

Their approach briefly highlights core ideas of concepts in a broader interdisciplinary framework to guide a more effective deep dive thereafter.

The learning journey starts with the purity of concepts, reveals its power to connect biological entities in structure and time, and finally introduces concepts to tightly align abstraction with reality. (5/9)

Access this OA title for free or get a hard copy at openbookpublishers.com/books/1
👇🧵(1/9)

#systems #biology #Workbook #engineering #biochemical #metabolic #pedagogic #mathematical #physics

Last updated 2 years ago

CellBioNews · @cellbionews
34 followers · 711 posts · Server scientificnetwork.de
Mark Maguire · @MarkMaguire
826 followers · 2799 posts · Server mastodon.ie

I somehow missed Rare Disease Day yesterday, 28th February, which is a bit of a faux pas for a carrier of a rare disease gene (Classic PKU) and a dad to a kid with PKU. I wouldn’t have missed it on the Other Site. Isolated communities excel at using Twitter to cohere around spotlight days or months. But in good news today I’ve found two other Mastodonians using the PKU #. Our rare community just grew a little.

#RareDisease #rarediseaseday #PKU #phenylketonuria #metabolic #pkulife

Last updated 2 years ago