preLights · @preLights
584 followers · 25 posts · Server biologists.social

Small but mighty: Sneider and colleagues demonstrate the impact of tissue stiffness on extracellular vesicle-mediated metastasis in breast cancer.

Great team effort from preLighters Jade Chan & Yohalie Kalukula – check it out! 👀

👉 prelights.biologists.com/highl

#wirtzlab #preprint #prelight #ecm #evs #metastasis #cancer

Last updated 1 year ago

Coffee ⏚ · @coffee
27 followers · 191 posts · Server g33ks.coffee

A large problem in treating is that tumor cells can break loose and travel through the body, founding new tumors. This is known as . A single tumor can usually be operated, but when they start growing all over, the cancer becomes very hard to fight.

Scientists have now uncovered a part of the mechanism that makes those tumor cells travel. There's a known as that normally hangs out in a part of the cell called the endoplasmatic reticulum, where it helps large proteins to fold the right way. However, when the cell is under stress, or becomes cancerous, GRP78 can travel to the cell's nucleus and turn certain on and off. Several of those genes control the cell's willingness to travel.

This discovery opens up new avenues of and possible treatments.

medicalxpress.com/news/2023-07

#cancer #metastasis #protein #grp78 #genes #research

Last updated 1 year ago

Furqan Shah · @furqanshah
51 followers · 78 posts · Server mstdn.science

formation in the alveolar , with exposure and osteolytic . Scanning electron microscopy, Micro-Raman spectroscopy, and energy dispersive X-ray spectroscopy reveal Mg-rich, rhomboidal nodules (200 nm to 2.4 µm) within the lacuno-canalicular space. Mg-whitlockite formation in lacunae is multifactorial in and suggests altered bone .

Read more:
doi.org/10.1016/j.micron.2023.

#magnesium #whitlockite #bone #bisphosphonate #skeletal #metastasis #osteocyte #nature #biomineralization #biology #pathology #Science

Last updated 2 years ago

Howard Smith MD, AM · @Drhowardsmith
1 followers · 307 posts · Server masto.nyc

Nicotine Associated with Breast Cancer Spread: Best Of: 1/2021:
North Carolina oncologists report that former or current cigarette smokers are significantly more likely to suffer breast cancer lung metastases compared with non-smokers.
youtu.be/Knip3Vws2AY

#breastcancer #metastasis #nicotine

Last updated 2 years ago

jobRxiv · @jobRxiv
832 followers · 1619 posts · Server mas.to
stjuderesearch · @stjuderesearch
21 followers · 51 posts · Server ohai.social

find ways to thrive in harsh environments. have new clues about how those succeed and how to potentially stop them. “The overarching goal of our lab is to understand how works so that we can eventually target it therapeutically,” says Dr. Myriam Labelle of . Learn more. bit.ly/3ZUjLvN

#metastatic #cancercells #stjude #scientists #cells #metastasis #oncology #stjuderesearch #womeninscience #whm

Last updated 2 years ago

Furqan Shah · @furqanshah
45 followers · 73 posts · Server mstdn.science

formation in the alveolar , with exposure and . Scanning electron microscopy, Micro-Raman spectroscopy, and energy dispersive X-ray spectroscopy revealed Mg-rich, rhomboidal nodules (~200 nm to ~2.4 µm) within the lacuno-canalicular space. Mg-whitlockite formation within lacunae is multifactorial in and suggests altered bone .

Read more:
doi.org/10.1016/j.micron.2023.

#magnesium #whitlockite #bone #bisphosphonate #osteolytic #skeletal #metastasis #osteocyte #nature #biomineralization #biology #pathology

Last updated 2 years ago

IMAGE Lab · @LabPhan
2 followers · 63 posts · Server qoto.org

We are hiring! @INCITeCentre is growing and we are looking for talent to join our team to look into the dark space of tumours. Please DM for more info. Please RT 🙏
---
RT @INCITeCentre
🚨 JOB ALERT🚨 Interested in working on , cell , and using high resolution ? Apply to us!
@LabPhan @Timpson_Lab @GarvanInstitute
DM if interested!

https://www.natu…
twitter.com/INCITeCentre/statu

#autoimmunity #imaging #recruiting #intravital #tumor #cancer #incite #Dormancy #metastasis

Last updated 2 years ago

jobRxiv · @jobRxiv
803 followers · 1332 posts · Server mas.to
Anna Obenauf · @Obenaufa
222 followers · 60 posts · Server mstdn.social

RT @JInsuaRodriguez
We are looking for a new member for the Early Career Leadership Council of the MRS!

If you're an early/mid career scientist/clinician and want to be part of a dynamic international team committed to research, apply! twitter.com/MetastasisRS/statu

#metastasis

Last updated 2 years ago

IMP · @IMPvienna
511 followers · 160 posts · Server mstdn.science

Beug Foundation’s Prize for Metastasis Research opened their 2023 call: young scientists are invited to apply with an original project on in Europe. Join the many outstanding awardees selected since 2011!
👉🏽 beugstiftung-metastase.de/appl

#cancer #metastasis #research

Last updated 2 years ago

Carolyn King · @ImmunologyKing
306 followers · 433 posts · Server mstdn.science

RT from the fabulous Ana Correia @alpcorreia

Thrilled to share my Perspective on how selectively restrains the growth of metastases - an exciting avenue for developing for long-lasting control of
Thanks Lucy Bird and @NatRevImmunol for the opportunity!
👉rdcu.be/c4539

#tissueimmunity #immunotherapies #metastasis

Last updated 2 years ago

Anna Obenauf · @Obenaufa
222 followers · 60 posts · Server mstdn.social

RT @emiliocasanova9
Call for applications for the Beug Foundation’s Prize for Metastasis Research 2023.
Apply here
beugstiftung-metastase.de
Please, RT

#prize #metastasis #cancer

Last updated 2 years ago

Biology Open · @BiologyOpen
309 followers · 55 posts · Server mstdn.science
Howard Smith MD, AM · @Drhowardsmith
1 followers · 307 posts · Server masto.nyc

Stopping Breast Cancer Spread:
Israeli researchers have shown that malignant cells penetrate blood vessels with micro drills they call invadopodia. Now discovery of a peptide protein that blocks invadopodia formation.
youtu.be/HJqsTYYKtI0

#breastcancer #metastasis #invadopodia #pyk2 #coractin

Last updated 2 years ago

Mutant Mouse Reso&Rsrch Center · @MMRRC
29 followers · 21 posts · Server mstdn.science

A new target to stop about 90% of cancer deaths (preventing ) was found with immunodeficient . Potential research opportunities are opened to slow or stop cells.

scitechdaily.com/new-study-unc

#metastasis #mice

Last updated 2 years ago

UC Davis Mouse Biology · @mousebiology
43 followers · 22 posts · Server mstdn.science

A new target to stop about 90% of cancer deaths (preventing ) was found with immunodeficient . Potential research opportunities are opened to slow or stop cells.

scitechdaily.com/new-study-unc

#metastasis #mice

Last updated 2 years ago

C. Harris Floudas · @chfloudas
68 followers · 326 posts · Server mstdn.social

RT @rio_sugimura: RT @Lo_Zanzi@twitter.com

! Beta-glucans induce training of interstitial macrophages via increased S1P sphingolipid induction (no mTOR or HIF1a invol), fragmentation/ROS production & protects against lung ! @NatImmunol@twitter.com doi.org/10.1038/s41590-022-013

🐦🔗: twitter.com/Lo_Zanzi/status/16

#oncology #metastasis #tumor #mitochodrial #lung #immunometabolismpower

Last updated 2 years ago

In a new study from Yale Cancer Center, Don Nguyen, PhD, says produced by blood vessels in the brain may help cells form and evade treatment. Researchers found residual cells remain even with good drug penetration.
medicine.yale.edu/news-article

#laminin #cancer #metastasis #tumor #medtwitter

Last updated 2 years ago

Theoretical Biophysics · @TheoBiophysics
85 followers · 162 posts · Server mas.to

RT @mathoncoblog@twitter.com

Likely our last blog post this year. Here Saumil Shah working with @EvolTheoArne@twitter.com and @_michael_raatz@twitter.com describe the latest work using to explore how impacts and treatment:
mathematical-oncology.org/blog

🐦🔗: twitter.com/mathoncoblog/statu

#metastasis #plasticity #MathOnco

Last updated 2 years ago