#iTHiNKLabs Episode 281🔴https://rb.gy/4wnby

Focus:

#COVID #VivekRamaswamy #Ukraine #Trump #M10Booker #Gabon #Education #Montana #Immigration #Texas #Twitter #Oregon #Jobs #Florida #COVID19 #Russia #Medicine #Military #MitchMcConnell #Negotiation #LongCovid #Security #Africa #Metformin #France #Politics #China #Mastodon #Niger #Fediverse #BurkinaFaso #Law #Guinea #News #Mali #SocialMedia #Health #ElonMusk #USA #Aging #Business #Indiana #CyberSecurity #Tennessee #Science #CybercrimeTreaty▼

From Dr Ruth Ann Crystal's #COVID newsletter

"Across the United States #hospital admissions with COVID are up 22%. More disturbingly, hospital admissions for #children under the age of one with COVID are increasing

"If you are exposed to a person who has COVID, you should #test every 48 hours x 3 (i.e. day 1, 3, 5, 7) if you have no symptoms. If you have any symptoms, test every 48 hours at least two times (day 1, 3, 5). It is best to wear an #N95 or #KN95 mask for 10 days after exposure to protect others and to isolate if you feel sick. #Paxlovid and/or #Metformin may be appropriate for some people."

1/n

https://drruth.substack.com/p/covid-news-and-more-82623?utm_medium=email

@kudra
If you followed @thelancetinfdis & @thelancet you can read & analyze all publications on #metformin & #COVID latest studies and you have all your answers by email the researchers
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00299-2/fulltext#:~:text=Interpretation,low%2Dcost%2C%20and%20safe.
https://www.thelancet.com/action/doSearch?type=quicksearch&text1=Metformin++covid&field1=AllField&journalCode=laninf&SeriesKey=laninf .

From 25 Aug: EMBER Study: Metformin Use Linked to Vitamin B12 Deficiency - https://www.hcplive.com/view/metformin-use-linked-to-vitamin-b12-deficiency #metformin #metformin-and-vitamin-b12 #metformin-side-effects #type-2-diabetes #t2d

Die aktuellen Varianten lösen weiterhin Verläufe auf, die ohne #Impfung schwerer verlaufen als mit. Und wer #Paxlovid nimmt, verkürzt Krankheitsdauer und -schwere. #Metformin verringert zudem #LongCOVID-Risiko.

Die Möglichkeit, an entsprechende Medikamente (und im Herbst Booster) zu kommen, ist allerdings viel geringer als sich auf der Straße harte Drogen zu besorgen.

As I ponder whether I might be developing Type 2 Diabetes -- https://perks.optum.com/blog/metformin-what-to-expect-day-1-week-1-month-1-and-beyond

#metformin #diabetes

There is a long list of potential treatments, antivirals, immunomodulators, anticoagulants or platelet inhibitors,modulators of metabolism, neurological function or other organ-specific functions. A recent study in #LongCovid is modifiable & successful clinical trials of the condition are possible; #metformin given during acute infection reduces the risk of developing LC
@thelancetinfdis
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00440-1/fulltext

Dr. Griffin joked #metformin (an inexpensive diabetes drug) is now considered a “poor man’s #Paxlovid,” which goes into the next paper: metformin reduced viral load (aka RNA copy number), but only by a teeny bit. The hosts were NOT impressed by the impact, and Dr. Racaniello wanted them to look at infectious virus. Dr. Griffin wryly observed that he wouldn’t be surprised if eventually, rich people got Paxlovid and poor people got the crappier metformin. 😅

#TWiVTLDR 14/

…An earlier #metformin study used 1500mg as a dose and they actually had to stop the study because there were too many side effects. People couldn’t tolerate it.

Metformin mostly helped people under 45, the unvaccinated, and those with BMI over 30.

#TWiVTLDR 13/

A pre-print they discussed before is now published! Outpatient treatment with metformin helped reduce #LongCOVID risk by about 41%, with an absolute reduction of 4%. Dr. Griffin notes that the amount of #metformin used in this study needed to be titrated - from 500mg to 1000mg over 2 weeks. Which means if you want metformin, you need to work closely with your doctor on dosing, they can’t just give you a script for the whole regimen at once…

#TWiVTLDR 12/

Metformin, a drug known for a century and used to treat type 2 diabetes, has shown in recent findings to reduce muscle atrophy and muscular fibrosis. It could help in particular the elderly in recovering from injury. See http://www.neat-news.com/2023/07/208.php. #metformin #muscle

Never stopped masking, staying home, etc... #COVID found me.

Any know any #CovidAware doctors in #michigan that might do a video visit and prescribe #metformin ?

#CovidIsNotOver

Diabetes drugs like #Wegovy, #Mounjaro and #Ozempic are in the news for their notable side effect: #weightloss. But they're super expensive.

An older, more well-studied stand-by #diabetes drug offers many of the same benefits at a fraction of the cost: #metformin.

This physician/writer analyzes and compares: https://medium.com/wise-well/how-metformin-may-help-you-live-longer-and-healthier-b50e9c31139f

Common diabetes drug metformin could protect against long COVID

https://theconversation.com/common-diabetes-drug-metformin-could-protect-against-long-covid-207460

#TheConversation #Metformin #LongCovid #COVID19

#Metformin, a drug commonly used to treat diabetes, may prevent the development of “long #COVID,” according to a clinical trial published in The Lancet Infectious Diseases.

http://spr.ly/6016PzQZE

Reappraisal of metformin efficacy in the treatment of type 2 diabetes: a meta-analysis of randomised controlled trials

https://pubmed.ncbi.nlm.nih.gov/22509138/

“Although #metformin is considered the gold standard, its benefit/risk ratio remains uncertain. We cannot exclude a 25% reduction or a 31% increase in all-cause mortality. We cannot exclude a 33% reduction or a 64% increase in cardiovascular mortality. Further studies are needed to clarify this situation.”

“Older treatments, including #insulin, do not affect #LongTermOutcomes. In what might result in a shake-up in our approach to type 2 #diabetes, #metformin was not found to be more effective than standard treatment to prevent important outcomes, which echoes previous findings and may cause it to be removed as a cornerstone of treatment”

No ciekawe, ciekawe 🤔
Czy #metformina #metformin może okazać się panaceum XXI wieku?
https://spidersweb.pl/plus/2023/07/niesmiertelnosc-dolina-krzemowa-lekarstwo

@wattevans
@ralf @retrohondajunki @morgfair

Statistically speaking, metformin is well-tolerated; most people's don't get side effects. There people who do are mostly diarrhea that is either so mild that they ignore it, or it goes away after a week or two. Contrary to popular belief, it does NOT damage your kidneys. Of course, everyone's different; a small fraction of people may be allergic to it.

Disclaimer: I AM a doctor, but not YOUR doctor, and this is not medical advice.

#metformin

Diabetes drug can
Reduce long Covid risk by forty
Metformin works twice

#metformin #longcovid #covid #diabetes #haiku #poetry

http://www.medicalnewstoday.com/articles/a-common-diabetes-drug-could-lower-long-covid-risk-by-40