Yeah ! Got a pilot grant to develop a /Cas9 @nanopore protocol to obtain full haplotypes !

#crispr #marmoset #mhc

Last updated 2 years ago

The EMBO Journal · @embojournal
424 followers · 133 posts · Server sciencemastodon.com

DNA sensing via the /STING pathway regulates function and class I presentation to promote activation - with implications for the pathology of idiopathic pulmonary fibrosis

Silke Meiners et al ForschungszentrumBorstel@norden.social

embopress.org/doi/10.15252/emb

#cgas #immunoproteasome #mhc #antigen #Tcell

Last updated 2 years ago

Dr. Orna Izakson ND, RH(AHG) · @DrOrna
488 followers · 398 posts · Server newsie.social

Great thread by @jeffgilchrist explaining some basic immunology and how newer COVID strains hijack it — with invisibility glamours and look-away spells. (Those are my words. He’s very scientific.)

mstdn.science/@jeffgilchrist/1

#COVID19 #covid #immuneevasion #mhc #nkcells #naturalkillercells

Last updated 2 years ago

How actively suppresses and evades your system [Part 1]

This thread highlights multiple methods that the virus uses to help keep people including -I and , of Natural Killer (NK) cells, and reprogramming of . 🧵 1/

The one page web view is available here: pingthread.com/thread/16113332

#covid #immune #reinfecting #mhc #Interferon #suppression #evasion #monocytes

Last updated 2 years ago

Dr. Orna Izakson ND, RH(AHG) · @DrOrna
464 followers · 364 posts · Server newsie.social

More science about Covid’s strategies for evading immune detection.

Preprint here: biorxiv.org/content/10.1101/20

system

#covid #COVID19 #mhc #cd8tcells #innateimmunity #immune

Last updated 2 years ago

The EMBO Journal · @embojournal
142 followers · 20 posts · Server sciencemastodon.com

Mechanical forces impair discrimination by reducing differences in receptor/peptide– off-rates

New article by Johannes Pettmann, Lama Awada et al

embopress.org/doi/10.15252/emb

#antigen #Tcell #mhc

Last updated 2 years ago

I am done with lab work (celebrating w new do) for my Marie Curie project @msca on and in . Now 💻. COVID almost destroyed this but even finishing a year after funds ran out I am determined to reach my goals. Thank you @dpz_eu @marissa_lima @estercsabino

#hybrids #mhc #marmosets

Last updated 2 years ago

Katharina Schmack · @KathaSchmack
311 followers · 84 posts · Server nerdculture.de

No evidence for link between C4 and !

An impressive study in ~70k blood samples fails to detect association between genes and protein at birth and schziophrenia later in life. This is interesting because the strongest genome-wide association for , found in the region, has so far been attributed to C4. May the search for other loci continue, I cannot wait to see the mystery of schizophrenia unfold!

medrxiv.org/content/10.1101/20

#complement #schizophrenia #medrxiv #c4 #mhc #gwas

Last updated 2 years ago

Ulli 🇪🇺 🏳️‍🌈 · @ulli
48 followers · 411 posts · Server norden.social