Heat shock during #Drosophila #embryogenesis results in maternal miRNA retention & downregulation of pre-MBT genes including Elba1, which may contribute to setting the stage for subsequent gene expression ➡️ https://www.embopress.org/doi/full/10.15252/msb.202211148
from Anita Öst, Linköping University #miRNA #GeneRegulation #SystemsBiology

DICER is one of the fundamental enzymes in your body, responsible for processing RNA into different forms, often involved with RNA silencing.

While we know how double stranded RNAs are processed, how DICER processes microRNAs is poorly understood.

Now, Seoul National University scientists have identified how it utilizes the GYM motif for processing, expanding our fundamental understanding.

#Biology #Microbiology #Genetics #RNA #Dicer #miRNA #Science #Scicomm

https://www.nature.com/articles/s41586-023-05723-3

#IDmastodon #Cardiomastodon #Clinicalreviews #SARSCoV2 Infection & #cardiovasculardiseases .Alterations in Circulating #miRNA Levels after Infection with #SARSCoV2 Could Contribute to the Development of Cardiovascular Diseases: What We Know So Far @IJMS_MDPI
📌 https://www.mdpi.com/1422-0067/24/3/2380
📌 https://www.mdpi.com/1422-0067/24/2

This just published from Jeff Chao's lab
@MolecularCell

"Single-molecule imaging reveals translation-dependent destabilization of mRNAs"

#mRNA #mRNADegradation #miRNA #translation #imaging #SingleMolecule

https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00033-3

When the bioRxiv came out (along with 2 others on similar topic), I wrote about it in my blog:

https://greenfluorescentblog.wordpress.com/2021/07/25/imaging-of-mirna-mediated-translational-repression-and-mrna-decay-at-single-molecule-resolution/

There are several additions in the print version, e.g. adding miR-21. but its just 1st impression. Have to read it.

RT @MarkusHoffmann2@twitter.com

Excited to introduce #circRNAsponging, a pipeline that systematically assesses the potential of circRNAs as biomarkers for diagnosis and treatment. Read our full article http://doi.org/10.1101/2023.01.19.524495 #miRNA #sponging #circRNA #ceRNA @itisalist@twitter.com @nico_trummer@twitter.com @janbaumbach@twitter.com @kahoadley@twitter.com

🐦🔗: https://twitter.com/MarkusHoffmann2/status/1617764223718940672

Our preprint with https://www.twitter.com/MorganMacKenz12 , the Soleimani lab at Nephrology https://www.twitter.com/UNMHSC, https://www.twitter.com/UNM & the research staff at https://www.twitter.com/UNM_CTSC regarding simultaneous short non-coding e.g. #mirna & long coding or noncoding #RNA on the long read sequencing #nanopore platform @nanopore https://www.twitter.com/nanopore.
Tootorial to follow! #sequencing #transcriptomics #lncRNA #epigenetic
#bioinformatics #NGS
https://qoto.org/@biorxivpreprint/109532523959529874

https://twitter.com/ChristosArgyrop/status/1604653631671652352?t=ighGK-HP8usj-YB-1MYFrQ&s=09

RT @neuroimmune_usp@twitter.com

Congratulations @carol_zinhap@twitter.com for the wonderful PhD defense on your work with #zikv and #miRNA in #astrocytes. Beautiful work! We are so proud of you. We wish you tons of success with @QuintanaLabHMS@twitter.com during your post-doc 👏👏👏

🐦🔗: https://twitter.com/neuroimmune_usp/status/1600145943185297408

RT @PSarkies@twitter.com

Really cool new preprint on #miRNA #evolution and great thread explaining it @BastianFromm@twitter.com https://twitter.com/BastianFromm/status/1596063697587372032

🐦🔗: https://twitter.com/PSarkies/status/1596144137249914880

Roles of RNA silencing in viral and non-viral plant immunity and in the crosstalk between disease resistance systems
#RNASilencing #BioticStress #miRNA #siRNA #Plants
https://www.nature.com/articles/s41580-022-00496-5

@glycocode this is such a cool paper on #glycotime #rna #miRNA - so many miRNAs that upregulate expression of glyco-genes. Congratulations Lara and team! 🥳

RT @glycocode@twitter.com

Our initial work on #miRNA regulation of #glycotime followed this paradigm and we found that microRNA are major regulators of the glycome.
https://www.pnas.org/doi/10.1073/pnas.1321524111

🐦🔗: https://twitter.com/glycocode/status/1590406601164619778