Hi #ScienceMastodon! Check out the last Research Highlight from Issue 17 of JCS: Ke Hu and colleagues at Arizona State University mess with microtubule-associated proteins in Toxoplasma gondii to answer whether the distinct helical motility of this apicomplexan parasite arises from the spiral arrangement of its remarkably stable cortical microtubules.
#CellBiology #microtubules #parasitology

Function follows form of cortical microtubules in Toxoplasma gondii
https://journals.biologists.com/jcs/article/136/17/e136_e1702/327904/Function-follows-form-of-cortical-microtubules-in

Deciphering the 'highway code' of our #cells: Team identifies key mechanism in #regulation of #microtubules.

https://phys.org/news/2023-09-deciphering-highway-code-cells-team.html

Happy Monday again, #ScienceMastodon! The first Research Highlight from JCS Issue 16 features a paper from Toshiyuki Oda and colleagues at the Universities of Yamanashi and Tokyo, using the unicellular algae Chlamydomonas reinhardtii to break down roles of tubulin modifications in ciliary/flagellar motility. #CellBiology #microtubules #flagellates

Roles of ciliary tubulin PTMs in Chlamydomonas reinhardtii
https://journals.biologists.com/jcs/article/136/16/e136_e1601/325932/Roles-of-ciliary-tubulin-PTMs-in-Chlamydomonas

#DonaldHoffman - #QuantumPhysics of #Consciousness

https://www.youtube.com/watch?v=tio1vJoTeKY&ab_channel=CloserToTruth

#Philosophy #PhilosophyOfScience #PhilosophyOfMind #Mind #TheMind #Neuroscience #Neurophysiology #QM #QuantumMechanics #Microtubules #QuantumState #Qualia #IdentityTheory #CloserToTruth #RobertKuhn

Fans of #Celegans will appreciate today's Research Highlight from Journal of Cell Science: Asako Sugimoto and colleagues identify unconventional subunits of the C. elegans γTuC microtubule nucleating complex acquired during its evolution, with important roles in embryonic development and germline maintenance. #microtubules #evolutionarybiology

Discovering divergent γTuC subunits in C. elegans
https://journals.biologists.com/jcs/article/136/13/e136_e1303/323431/Discovering-divergent-gTuC-subunits-in-C-elegans

Hello! A new intro for a new instance.

I lead a research group trying to figure out axonal transport and neurodegeneration. A big emphasis on the microtubules and their motors, but really the transport of anything that doesn't have a membrane around it. For this we use a lot of single molecule methods and live cell imaging. I also post about research culture.

#introduction #kinesin #dynein #microtubules #neurodegeneration #AxonalTransport #neurobiology #SingleMolecule #CellBiology

How does #centrosome #amplification -common in #cancer- promote #cellmigration through confined spaces?
Susana Godinho and colleagues show that it alters intracellular organization via effects on #tubulin #acetylation and #organelle transport along #microtubules
https://www.embopress.org/doi/full/10.15252/embj.2022112812

I was at #EMBL when #TaraOcen project started ... It definitely also was #EricKarsenti wanting some science fun on a boat after years with #microtubules and #microscopes only... #MarineBiology #oceanograpy #TheOtherSideOfTheMoon

The inspiring story of the Tara and its 20-year message from the corals https://www.nature.com/articles/d41586-023-01826-z

Yuanjun Li, Yonglu Tian, Xiayuhe Pei, Ning Huang, Jianguo Chen and colleagues find that SCG10 promotes dynamic microtubules in peripheral axons.

Highlight: https://journals.biologists.com/jcs/article/136/12/e136_e1203/319490/SCG10-promotes-dynamic-microtubules-in-peripheral

Article: https://journals.biologists.com/jcs/article/136/12/jcs260490/319484/SCG10-is-required-for-peripheral-axon-maintenance

#CellBiology #microtubules #cytoskeleton #neurons

As Stuart Hameroff and Sir Roger Penrose suggest, Tryptophan residues in #microtubules influence #consciousness. In this 3D print of Microtubule 3J2U, we can see how TRP residues (tinted dark) interconnect adjacent #Tubulin molecules. #structuralbiology
https://biologicmodels.com/pdb/3j2u/microtubule-3j2u/?aiEnableCheckShortcode=true

The next MiQ talk will be on Wednesday 7th June 2023 at 15:00 UTC (8:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST / 20:30 IST / 23:00 CST).

Speakers:

Beth Lawrence (Zanic lab) - Vanderbilt University
CLASPs stabilize the intermediate state between microtubule growth and catastrophe

Julie Welburn - WTCCB Edinburgh
Predicting pathogenic mutations in tubulin

Details https://mechanochemistry.org/whatson/MiQ/

#CellBiology #MotorHeads #Microtubules #Cytoskeleton

Behind the #formation and protection of #microtubules.

#mitosis #chromosomes #γ_TuRC

https://phys.org/news/2023-05-formation-microtubules.html

Referenced link: https://phys.org/news/2023-05-formation-microtubules.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-05-formation-microtubules.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1653058462622928896#m

Behind the formation and protection of #microtubules @RockefellerUniv https://rupress.org/jcb/article/222/3/e202204102/213828/A-nucleotide-binding-independent-role-for-tubulin https://phys.org/news/2023-05-formation-microtubules.html

The next MiQ talk will be on Wednesday 26th April 2023 at 15:00 UTC (8:00 PDT / 11:00 EDT / 16:00 BST / 17:00 CEST / 20:30 IST / 23:00 CST).

Speakers:

Laura Meißner (Diez lab) - B-Cube Dresden
Microtubule organisation by kinesins from a 3D perspective

Shashank Shekhar - Emory University
Reverse treadmilling: Barbed end depolymerization and pointed end depolymerization

https://mechanochemistry.org/whatson/MiQ/

#CellBiology #Seminar #Cytoskeleton #Microtubules #Motors

this fascinating, early episode of #TWIM discusses 2 papers that involve #microbial #electrochemistry (not sure where current amplification was mentioned wrt 2nd paper, but they did discuss conductivity in #microtubules constructed by a #bacterium
https://open.spotify.com/episode/2nK1bkhOjZc1v9nI0GWRGN?si=hCbSupBYS1iKVGLKtAK4Sg

Pseudo-#chromosome–length #genome assembly for the deep-sea #eel Ilyophis brunneus sheds light on deep-sea #adaptation.

#TUGBCP3 #ITGA #microtubules

https://phys.org/news/2023-03-pseudo-chromosomelength-genome-deep-sea-eel-ilyophis.html

Our #Featuredimage this week comes from Alexis Lomakin. The image ‘Cellular highways’ shows the nuclei, #microtubules and Golgi in rat liver epithelial cells. In our post, we find out more about Alexis’ research and #microscopy favourites.
https://focalplane.biologists.com/2023/03/22/featured-image-with-alexis-lomakin/

If you have an image that you would like to share in our ‘Featured image with’ post, drop us a message here or at focalplane@biologists.com.

#cellbiology #microscopy #sciart

As Stuart Hameroff and Sir Roger Penrose suggest, Tryptophan residues in #microtubules influence #consciousness. In this 3D print of Microtubule 3J2U, we can see how TRP residues (tinted dark) interconnect adjacent #Tubulin molecules. #structuralbiology
https://biologicmodels.com/pdb/3j2u/microtubule-3j2u/?aiEnableCheckShortcode=true

Like a flexible Lego railway track: How stable #microtubules form within #cells.

https://phys.org/news/2023-03-flexible-lego-railway-track-stable.html

Referenced link: https://phys.org/news/2023-03-flexible-lego-railway-track-stable.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-03-flexible-lego-railway-track-stable.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1633900978771509271#m

Like a flexible Lego #railwaytrack: How stable #microtubules form within cells https://www.life-science-alliance.org/content/6/5/e202201714 https://phys.org/news/2023-03-flexible-lego-railway-track-stable.html