#microRNAs slow translating #ribosomes to prevent protein #misfolding in eukaryotes
Hiroaki Sako, Tadashi Yamamoto and colleagues
The unusual presence of #miRNAs targeting protein-coding sequences is shown to influence ribosome speed, thereby allowing time for accurate #polypeptide folding during protein translation.
https://www.embopress.org/doi/full/10.15252/embj.2022112469
#micrornas #ribosomes #misfolding #miRNAs #polypeptide
Researchers discover how #mitochondria call for help when under #stress.
#signalling #proteins #misfolding #chaperonins #transcriptomics #DNAJA1 #HSP70
#mitochondria #stress #signalling #proteins #misfolding #chaperonins #transcriptomics #dnaja1 #hsp70