The EMBO Journal · @embojournal
439 followers · 156 posts · Server sciencemastodon.com

A -Cas9-tagging approach to induce -specific segmental : targeted assembly of ectopic at endogenous repeats - a way to recapitulate and study specific disease-associated events in human cells

@McClellandLab
embopress.org/doi/10.15252/emb

#crispr #Chromosome #aneuploidies #kinetochores #missegregation

Last updated 2 years ago

The EMBO Journal · @embojournal
432 followers · 154 posts · Server sciencemastodon.com

How do cancer-specific chromosome gains/losses contribute to ?
Susanne Lens and collaborators at UMC Utrecht describe a -based strategy for inducing of selected , as tool for modeling specific

embopress.org/doi/10.15252/emb

#oncogenesis #kinesin #mitotic #missegregation #Chromosomes #aneuploidies

Last updated 2 years ago

The EMBO Journal · @embojournal
301 followers · 37 posts · Server sciencemastodon.com

How do cells adapt to high rates of ?

Chris Campbell and coworkers @maxperutzlabs define serial alterations from specific , refinement, point , to loss of beneficial copy number alterations

embopress.org/doi/10.15252/emb

#yeast #Chromosome #missegregation #aneuploidies #karyotype #Mutations

Last updated 2 years ago