American Naturalist · @ASNAmNat
1969 followers · 188 posts · Server ecoevo.social#Mitochondrial genes are often used to test for #positiveSelection on #energetics, but do the stories supported by #dN/dS ratios hold up? Zwonitzer et al. reexamined seven case studies and found evidence for positive and relaxed #selection, but not always according to the previous hypotheses.
Read now ahead of print!
https://www.journals.uchicago.edu/doi/10.1086/725805
#mitochondrial #positiveselection #energetics #dn #Selection
The EMBO Journal · @embojournal
554 followers · 288 posts · Server sciencemastodon.com
#Exosomal secretion of #mitochondrial DNA in response to #caspase1 activation promotes #inflammation in Behçet's syndrome
Hyota Takamatsu, Atsushi Kumanogoh and coworkers
#exosomal #mitochondrial #caspase1 #inflammation
ISOGG · @isogg
337 followers · 168 posts · Server genealysis.social“We attribute this similarity in Paleolithic technology, as well as the phylogenetic relationships of D4h sub-lineages in China, the Americas, and Japan, to a probable Pleistocene connection among these regions.” #isogg #dna #geneadons #nativeamericandna #mtdna #mitochondrial https://www.iflscience.com/mystery-of-where-native-americans-came-from-could-be-solved-with-dna-70540
#isogg #dna #geneadons #nativeamericandna #mtdna #mitochondrial
The EMBO Journal · @embojournal
552 followers · 286 posts · Server sciencemastodon.com
A mitochondrial #EglN1/#PHD2-#AMPK-alpha axis drives #breastcancer progression by enhancing metabolic adaptation to #hypoxic stress
#Hypoxia-induced EglN1-#CaMKK2 interaction on #mitochondrial safeguards AMPKα activation and #metabolic homeostasis during breast cancer growth
#egln1 #ampk #breastcancer #hypoxic #Hypoxia #camkk2 #mitochondrial #metabolic
CellBioNews · @cellbionews
111 followers · 1826 posts · Server scientificnetwork.deResearchers construct first global map of #insect #mitochondrial #genetic #diversity.
https://phys.org/news/2023-08-global-insect-mitochondrial-genetic-diversity.html
#insect #mitochondrial #genetic #diversity #genomics #phylogenetics
TrangAston :verified: · @CastlTrAstonDrs
1425 followers · 3073 posts · Server med-mastodon.com
Targeting #mitochondrial function may represent a new therapeutic approach for #LongCovid patients
https://www.mdpi.com/1422-0067/24/9/8034
The EMBO Journal · @embojournal
532 followers · 265 posts · Server sciencemastodon.com
#MARCH5-dependent #NLRP3 #ubiquitination is required for #mitochondrial NLRP3-NEK7 complex formation and NLRP3 #inflammasome activation
https://www.embopress.org/doi/full/10.15252/embj.2023113481
#march5 #nlrp3 #ubiquitination #mitochondrial #inflammasome
CellBioNews · @cellbionews
102 followers · 1774 posts · Server scientificnetwork.de'Spider-like' #mitochondrial structure initiates #cell-wide #stress response.
https://phys.org/news/2023-08-spider-like-mitochondrial-cell-wide-stress-response.html
#mitochondrial #cell #stress #dele1 #isr
The Ocean Cowboy · @Oceancowboy
380 followers · 130 posts · Server kolektiva.social~190 000 years ago, the #human population capable of #reproduction dropped from ~10k to 600. #Mitochondrial #Eve was born here; she is the #female #ancestor from which we are all descendants.
#human #reproduction #mitochondrial #eve #female #ancestor
· @drjudystone
860 followers · 935 posts · Server mstdn.scienceQuestion for #IDTwitter expats on Mastodon #IDPharm - do you know any Rx for #quinolone related neuro toxicity-- Pain and peripheral neuropathy? Supplements for #mitochondrial disorders? Any centers studying this? Thanks
#IDtwitter #idpharm #quinolone #mitochondrial
The EMBO Journal · @embojournal
500 followers · 241 posts · Server sciencemastodon.com
How do mitochondria obtain the #ribonucleotides they need for organellar transcription?
Thomas MacVicar, Thomas Langer and colleagues show key fueling role of #mitochondrial #nucleoside diphosphate kinase #NME6 that phosphorylates #pyrimidine nucleosides
https://www.embopress.org/doi/full/10.15252/embj.2022113256
#ribonucleotides #mitochondrial #nucleoside #nme6 #pyrimidine
CellBioNews · @cellbionews
70 followers · 1569 posts · Server scientificnetwork.deNucleo-cytoplasmic interaction in seedless cybrid #citrus.
#mitochondrial #genome #chloroplast
https://phys.org/news/2023-07-nucleo-cytoplasmic-interaction-seedless-cybrid-citrus.html
#citrus #mitochondrial #genome #chloroplast
JIPB · @JIPB
42 followers · 183 posts · Server mstdn.science
To know where we're going, we need to know where we've been.
Hu et al. reveal #genome-scale #angiosperm #phylogenies based on #nuclear, #plastome, & #mitochondrial datasets.
https://doi.org/10.1111/jipb.13455
@wileyplantsci
#JIPB #PlantSci #PlantScience
#genome #angiosperm #phylogenies #nuclear #plastome #mitochondrial #JIPB #plantsci #plantscience
CircadianHealth · @CircadianHealth
56 followers · 140 posts · Server med-mastodon.com
• Inadequate #sleep is associated with an increased risk of #metabolic disorders.
• Mitochondrial metabolism lies at the heart of a homeostatic sleep-regulatory mechanism.
• Sleep need is encoded in the excitability state of sleep-control neurons in the central fly brain.
• #Mitochondrial ROS promotes sleep by acting on a redox-sensitive potassium channel subunit.
• Mitochondrial ROS modulates the activity of sleep-control #neurons
https://www.sciencedirect.com/science/article/pii/S0959438823000582
#sleep #metabolic #mitochondrial #neurons
The EMBO Journal · @embojournal
451 followers · 202 posts · Server sciencemastodon.com
#PERK signaling promotes #mitochondrial elongation by remodeling membrane #phosphatidic acid
Luke Wiseman and coworker
https://www.embopress.org/doi/full/10.15252/embj.2023113908
#perk #mitochondrial #phosphatidic
Brigitte Nerlich · @metaphornerd
465 followers · 581 posts · Server fediscience.orgToday's post is about two events that happened at the beginning of May, the sequencing of the #pangenome and first baby born using #mitochondrial replacement https://blogs.nottingham.ac.uk/makingsciencepublic/2023/05/17/mitochondrial-replacement-and-the-pangenome/
CellBioNews · @cellbionews
47 followers · 1034 posts · Server scientificnetwork.deUncovering hidden #mitochondrial #mutations in single cells.
https://phys.org/news/2023-04-uncovering-hidden-mitochondrial-mutations-cells.html
#mitochondrial #mutations #mtdna #imigseq
PLOS Biology · @PLOSBiology
4838 followers · 1356 posts · Server fediscience.org
In humans, #D2HGDH mutations cause developmental delay, seizures & #ataxia. Study shows that in nematode #Celegans, D2HGDH sustains #KetoneBody production to support embryonic viability; loss causes #mitochondrial defects & embryonic lethality #PLOSBiology https://plos.io/41r41k4
#plosbiology #mitochondrial #ketonebody #Celegans #Ataxia #d2hgdh
PLOS Biology · @PLOSBiology
4838 followers · 1353 posts · Server fediscience.org
In humans, #D2HGDH mutations cause developmental delay, seizures & #ataxia. Study shows that in nematode #Celegans, D2HGDH sustains #KetoneBody production to support embryonic viability; loss causes #mitochondrial defects & embryonic lethality #PLOSBiology https://plos.io/41r41k4
#plosbiology #mitochondrial #ketonebody #Celegans #Ataxia #d2hgdh
PLOS Biology · @PLOSBiology
4835 followers · 1349 posts · Server fediscience.org
In humans, #D2HGDH mutations cause developmental delay, seizures & #ataxia. Study shows that in nematode #Celegans, D2HGDH sustains #KetoneBody production to support embryonic viability; loss causes #mitochondrial defects & embryonic lethality #PLOSBiology https://plos.io/41r41k4
#plosbiology #mitochondrial #ketonebody #Celegans #Ataxia #d2hgdh