Really promising. Now please do humans..

Stem cell breakthrough cures Gorilla's arthritis in a first https://interestingengineering.com/culture/stem-cell-breakthrough-cures-gorillas-arthritis-in-a-first

#medicine #molbio #biotech

What is your prefered term for what we generally call Synthetic Biology? I know a few places are rebranding 🧬 :rna: :protein:

#SynBio #MolBio #genomics #genetics

Pictures Considered #58: Visualizing Introns

by Christoph
By reading sequences we easily detect stretches that code for pro­teins. We detect promoters, transcription factor binding motifs, start/stop signals for tran­scription, signals where introns are removed by splicing from primary transcripts (pre‑mRNA) to yield mature messenger RNA (mRNA), and much more. It wasn't always so easy.

Read more → https://tinyurl.com/4s5zebxr

#microbiology #introns #molbio #molecularBiology

The Biohacky hour continues to give us a place to discuss all issues around DNA assembly and SynBio work.

Join us Wednesday 4th of April for an informal chat about all of your cloning woes. And maybe get some useful feedback from people who have had similar problems before.

#SynBio #MolBio #Genomics

The Biohacky hour continues to give us a place to discuss all issues around DNA assembly and SynBio work.

Join us Wednesday 1st of March for an informal chat about all of your cloning woes. And maybe get some useful feedback from people who have had similar problems before.

#SynBio #MolBio #Genomics

An elegant paper from @nicolabiologist (on the Bird Site) for synthetic biologists to check out:

Tuning plant promoters using a simple split luciferase method for quantifying transcription factor binding affinity

https://www.biorxiv.org/content/10.1101/2023.02.13.528283v1

#SynBio #MolBio #Genetics

Your best quick and dirty protocols for high throughput(ish) DNA extraction from #Arabidopsis leaves. Hit me!

#plantscience #molbio

Please join the SynBio WA Network's seminar on CRISPR technologies next week (Friday 10th of February).

It will be a great chance to hear about local WA SynBio research and potentially win some prizes from our sponsors.

#SynBio #Genomics #MolBio #CRISPR

A new year and new Biohacky Hours are coming to Perth

Join us the first Wednesday of each month for an informal chat about all of your cloning woes. And maybe get some useful feedback from people who have had similar problems before.

First meeting will be on Wednesday the 1st Feb.

#SynBio #MolBio #Genomics

Cool discovery from a team at the Czech Academy of Sciences:

https://www.nature.com/articles/s41586-022-05584-2

An organism that can reassign stop codons, apparently!

#molbio #genes #transcription

If your DNA/plasmid is supercoiled and doesn't cut with your enzyme, try adding some Topoisomerase to loosen it up!

#cloning #molbio

Cellular Blockchains (kinda)!
Cells programmed to store memory of cellular events with self-assembling protein chains, visualized by fluorescent binding proteins.
Published in Nature Biotechnology.

#science #cellbio #molbio #biology #biotech

https://phys.org/news/2022-12-self-assembling-proteins-cellular-memories.html

New #preprint about PENSA, our flexible #OpenSource software package for comprehensive and thorough investigation of biomolecular conformational ensembles:

https://arxiv.org/abs/2212.02714

In three real-world examples, we show how it can be used to understand an #enzyme mechanism, #DNA #forcefield parameters, and #signaling in an #opioid #receptor.

Please share widely with the #MolecularDynamics #simulation #CompChem #MolBio #StructuralBiology #GPCR communities!
Feedback and ideas are always welcome.

Prev. unknown microbial pathway discovered that allows bacterial uptake of host folates evading antibiotics, particularly sulfa-drugs that inhibit folate synthesis.

https://rdcu.be/c06R3

Published in Nature Communications.

#microbiochem #AMR #molbio

Rodrigo, M.K.D., Saiganesh, A., Hayes, A.J. et al. Host-dependent resistance of Group A Streptococcus to sulfamethoxazole mediated by a horizontally-acquired reduced folate transporter. Nat Commun 13, 6557 (2022).
https://doi.org/10.1038/s41467-022-34243-3

2023 Human Genome Editing Summit announced for March 6-8 in London. Attendance free, streaming available.
#Genome #GeneEditing #MolBio
https://royalsociety.org/science-events-and-lectures/2023/03/2023-human-genome-editing-summit/

RT @lab_sengupta@twitter.com

As promised, excited to announce the tentative program of the Computational Biology lecture series (Hybrid Mode). There will be lectures, as well as hands-on sessions. Register to stay tuned. @CompBio_IIITD@twitter.com @IIITDelhi@twitter.com @lab_sengupta@twitter.com #Bioinformatics #genomics #genomics #molbio

🐦🔗: https://twitter.com/lab_sengupta/status/1595031353661493248

Join us in Newark! We're hiring a tenure-track assistant professor in comparative biology at NJIT. Perks include a diverse student population and a super supportive department! Hoping to bolster our current strengths spanning neurobiology and ecoevo.

Details: https://www.nature.com/naturecareers/job/assistant-professor-comparative-biology-new-jersey-institute-of-technology-njit-764296

@ecoevojobs #AcademicJobs #ScienceJobs #JobPosting #JobOffer #Job #Academia #EcoEvo #MolBio #CompBio

I am the lead #forensic pathologist for the BC Coroners Service, as well as a Clinical Assistant Professor of Pathology at UBC in Vancouver. I have a PhD in #biochemistry and #molbio. My research involved studying development of peacemaking and conducting cardiac myocytes using #stemcells. Although I am no longer in the lab, I enjoy collaborating on research involving cardiovascular pathology and sudden death.

I play cello, piano, and saxophone and especially enjoy jazz and chamber music.

Good discussion with a colleague on how we write about #biology to lay audiences, and how we may need to do more to generalise knowledge of molecular biology. E.g. a better general understanding of RNA, what it is, and how it works might’ve done wonders against vaccine hesitancy. We have some fantastic physics communicators in the mainstream, in TV and in popular science publications, maybe we should try to get more cell and molecular biologists there too? #SciComm #MolBio #CellBio