#IDMastodon #Molecularbiology #Microbiology #Immunology
Causal effects of the #gutmicrobiome on #COVID19 susceptibility and severity .This study found that some microbial taxa were protective factors or risky factors for #COVID19
18 known microbial taxa were causally associated with #COVID19.
Among them,
- 6 microbial taxa were causally associated with #COVID susceptibility .
- 7 microbial taxa associated with COVID19 severity ;
- 5 microbial taxa associatesdwith COVID19 hospitalization.
#IDMastodon #molecularbiology #microbiology #immunology #gutmicrobiome #COVID19 #COVID
'Using several high-throughput sequencing approaches, we show that the H/ACA complex is recruited to actively transcribed genes genome-wide, where it performs mRNA pseudouridylation. Moreover, we demonstrate that this modification reduces the rate of mRNA translation and that loss of dyskerin-mediated pseudouridylation results in global elevation of protein synthesis.'
#MolecularBiology #mRNA
#IDMastodon #molecularbiology #Viralimmunology Understanding the role of ORF8 is therefore critical in elucidating the mechanisms of #COVID19 . To efficiently infect, #SarsCoV2 uses a diverse set of strategies to evade #hostimmunity, accounting for its high pathogenicity and rapid spread throughout the #COVID19pandemic.
#IDMastodon #molecularbiology #viralimmunology #COVID19 #SarsCoV2 #hostimmunity #COVID19pandemic
Wang K, Prufer K, Krause-Kyora B, et al. (2023). High-coverage genome of the Tyrolean Iceman reveals unusually high Anatolian farmer ancestry. Cell Press. DOI: https://doi.org/10.1016/j.xgen.2023.100377 #OpenAccess #OA #Journal #Article #Science #Anthropology #Genetics #Biology #MolecularBiology #Genomics #Population #History #Ancient #DNA #AncientDNA #Chacolithic #Neolithic #Europe #Histodon #Histodons @science @histodon @histodons @anthropology
#openaccess #oa #journal #article #anthropology #genetics #biology #molecularbiology #genomics #population #history #ancient #science #dna #ancientdna #Chacolithic #neolithic #europe #histodon #histodons
Wang K, Prufer K, Krause-Kyora B, et al. (2023). High-coverage genome of the Tyrolean Iceman reveals unusually high Anatolian farmer ancestry. Cell Press. DOI: https://doi.org/10.1016/j.xgen.2023.100377 #OpenAccess #OA #Journal #Article #Science #Anthropology #Genetics #Biology #MolecularBiology #Genomics #Population #History #Ancient #DNA #AncientDNA #Chacolithic #Neolithic #Europe #Histodon #Histodons @science @histodon @histodons @anthropology
#openaccess #anthropology #histodon #histodons #neolithic #europe #oa #journal #article #science #genetics #biology #molecularbiology #genomics #population #history #ancient #dna #ancientdna #Chacolithic
Tip of the day: when using the "Hot Fusion", a ligation-less Gibson assembly protocol, the reaction mix needs to be prepared fresh. The T5 exonuclease does not seem to appreciate being frozen and thawed.
#gibsonassembly #cloning #molecularbiology
Location location location
"Here, we show that NET1 mRNA location in combination with the rate of its translation can influence the ability of competing domains to determine the targeting of the newly synthesized protein, by favoring binding to specific partners. This RNA-based partner-selection mechanism provides a robust means of controlling protein function."
#MolecularBiology #Translation #RNA
#translation #rna #molecularbiology
Drexel MCBG Thesis Defense 𧬠𧬠π§¬
Zahra Charania, MCBG, MS Candidate
Tuesday, August 8, 2023, 1:00 p.m. NCB, Room 11-101
Identifying conserved regions in lncRNA SChLAP1
Mentor: Dr. Srinivas Somarowthu
Drexel University College of Medicine, Department of Biochemistry and Molecular Biology
#GraduateStudent #GraduateStudies #BiomedicalScience #RNA #lncRNA #CellBiology #MolecularBiology #Biochemistry
#graduatestudent #graduatestudies #biomedicalscience #rna #lncrna #cellbiology #molecularbiology #biochemistry
RNA binding by the glucocorticoid receptor attenuates dexamethasone-induced gene activation. https://doi.org/10.1038/s41598-023-35549-y #ComputationalBiologyAndBioinformatics #MolecularBiology
#computationalbiologyandbioinformatics #molecularbiology
shameless self-plug: PlateMate now supports converting multiple plates between grid and long formats, and direct CSV downloads.
#shiny #r #bioinformatics #molecularbiology #lab #plate
Definitely the session we've all been waiting for- Integrating fossils and molecules to reconstruct the evolution of life in deep time!
#SMBE23 #SMBE2023 #paleo #evolution #MolecularBiology
#SMBE23 #smbe2023 #paleo #Evolution #molecularbiology
I enjoyed presenting my poster at the Ferrara #SMBE23 poster session. Lots of great conversations with interesting people and possible collaborations with people interested in #terrestrialization #evolution of #isopods.
#SMBE2023 #genomics #MolecularBiology
#SMBE23 #terrestrialization #Evolution #isopods #smbe2023 #Genomics #molecularbiology
Steinar Thorvaldsen , Ola HΓΆssjer, Estimating the information content of genetic sequence data, Journal of the Royal Statistical Society Series C: Applied Statistics, 2023;, qlad062, https://doi.org/10.1093/jrsssc/qlad062 #OpenAccess #OA #Journal #Article #Maths #Math #Mathematics #Statistics #Genetics #Biology #MolecularBiology #Data #Science #DataScience #AppliedStatistics #Academia #Academic #Academics @science @statistics @mathematics
#science #datascience #appliedstatistics #journal #maths #math #mathematics #statistics #genetics #openaccess #oa #article #biology #molecularbiology #data #academia #academic #academics
See this amazing venue for #SMBE2023.
#smbe2023 #Evolution #molecularbiology #conference #italy #ferrara
Zooming across time and space simultaneously with superresolution to understand how cells divide https://theconversation.com/zooming-across-time-and-space-simultaneously-with-superresolution-to-understand-how-cells-divide-203324 #Science #STEM #Microscopy #MolecularBiology #Biology #CellBiology #Research @science
#research #science #cellbiology #microscopy #molecularbiology #stem #biology
Hey, my first poll! Broadcasting to #biology #cellbiology #microbiology #molecularbiology folks out there.
What is the biological technique called, where you isolate single cells, and grow out single cell founded populations from those single cells, by using a single dilution into multiple independent containers, where the presence or absence of a single cell in those containers (and hence, the outgrowth of a population) is governed by the Poisson equation?
(would help my manuscript writing)
#biology #cellbiology #microbiology #molecularbiology
β³Oportunidad de #trabajo en #ciencia. Colegas de #Argentina llaman a cubrir un #postdoc para reparaciΓ³n del #ADN, #ciclocelular, y estabilida del #genoma.
#jobsinstem β‘οΈ Argentinean colleagues have an open call for #Postdocs in #dnarepair, #cellcycle regulation and #genome stability.
#biologia #proteinas #molecular #Mendoza #biology #CABA #genome #DNA #genomics #molecularbiology #proteins #biochemistry #conicet
#conicet #biochemistry #proteins #molecularbiology #genomics #dna #caba #biology #mendoza #molecular #proteinas #biologia #genome #cellcycle #dnarepair #Postdocs #jobsinstem #genoma #ciclocelular #adn #postdoc #argentina #ciencia #trabajo
π¨ We're expanding out #RNA Technologies team at Eleven Therapeutics! π¨
π https://tinyurl.com/RNA11Tx π
Come join us as a Senior Scientist and help develop the next generation of #RNA therapeutics! Our science couldn't be more cutting edge so don't miss this opportunity π
Please share!
#RNA #RNAtherapeutics #jobalert #hiring #MolecularBiology #MethodDevelopment #Scientist #RNArocks
#RNA #rnatherapeutics #jobalert #hiring #molecularbiology #methoddevelopment #Scientist #rnarocks
#IDMastodon #Molecularbiology #Drugdelivery #Drugdiscovery #COVID19pandemic has seen no single Rx or combination proven to effectively halt disease progression, & the effect of the massive worldwide vaccination campaign is waning & the thread of near-future surges of this pandemic by #Omicron subvariants. Pharmacological treatments that reduce the risk of progression from #SARSCoV2 infected patients are imperfect, and their efficacy is restricted to the early intervention .
#IDMastodon #molecularbiology #drugdelivery #DrugDiscovery #COVID19pandemic #omicron #SarsCoV2