TrangAston :verified: · @CastlTrAstonDrs
1434 followers · 3101 posts · Server med-mastodon.com


Causal effects of the on susceptibility and severity .This study found that some microbial taxa were protective factors or risky factors for
18 known microbial taxa were causally associated with .
Among them,
- 6 microbial taxa were causally associated with susceptibility .
- 7 microbial taxa associated with COVID19 severity ;
- 5 microbial taxa associatesdwith COVID19 hospitalization.

#IDMastodon #molecularbiology #microbiology #immunology #gutmicrobiome #COVID19 #COVID

Last updated 1 year ago

Thiago Carvalho · @cyrilpedia
1897 followers · 11178 posts · Server qoto.org

'Using several high-throughput sequencing approaches, we show that the H/ACA complex is recruited to actively transcribed genes genome-wide, where it performs mRNA pseudouridylation. Moreover, we demonstrate that this modification reduces the rate of mRNA translation and that loss of dyskerin-mediated pseudouridylation results in global elevation of protein synthesis.'

science.org/doi/10.1126/sciadv

#mrna #molecularbiology

Last updated 1 year ago

TrangAston :verified: · @CastlTrAstonDrs
1420 followers · 3038 posts · Server med-mastodon.com

Understanding the role of ORF8 is therefore critical in elucidating the mechanisms of . To efficiently infect, uses a diverse set of strategies to evade , accounting for its high pathogenicity and rapid spread throughout the .

#IDMastodon #molecularbiology #viralimmunology #COVID19 #SarsCoV2 #hostimmunity #COVID19pandemic

Last updated 1 year ago

Cosmin Saveanu · @cosminribo
143 followers · 526 posts · Server framapiaf.org

Tip of the day: when using the "Hot Fusion", a ligation-less Gibson assembly protocol, the reaction mix needs to be prepared fresh. The T5 exonuclease does not seem to appreciate being frozen and thawed.

pubmed.ncbi.nlm.nih.gov/255518

#gibsonassembly #cloning #molecularbiology

Last updated 1 year ago

Thiago Carvalho · @cyrilpedia
1850 followers · 9978 posts · Server qoto.org

Location location location

"Here, we show that NET1 mRNA location in combination with the rate of its translation can influence the ability of competing domains to determine the targeting of the newly synthesized protein, by favoring binding to specific partners. This RNA-based partner-selection mechanism provides a robust means of controlling protein function."

cell.com/molecular-cell/fullte

#translation #rna #molecularbiology

Last updated 1 year ago

Drexel MCBG · @drexelmcbg
96 followers · 3 posts · Server biologists.social

Drexel MCBG Thesis Defense 🧬 🧬 🧬

Zahra Charania, MCBG, MS Candidate

Tuesday, August 8, 2023, 1:00 p.m. NCB, Room 11-101

Identifying conserved regions in lncRNA SChLAP1

Mentor: Dr. Srinivas Somarowthu
Drexel University College of Medicine, Department of Biochemistry and Molecular Biology

#graduatestudent #graduatestudies #biomedicalscience #rna #lncrna #cellbiology #molecularbiology #biochemistry

Last updated 1 year ago

WikiPathways · @wikipathways
80 followers · 49 posts · Server fosstodon.org

RNA binding by the glucocorticoid receptor attenuates dexamethasone-induced gene activation. doi.org/10.1038/s41598-023-355

#computationalbiologyandbioinformatics #molecularbiology

Last updated 1 year ago

kdm9 · @kdm9
34 followers · 167 posts · Server genomic.social

shameless self-plug: PlateMate now supports converting multiple plates between grid and long formats, and direct CSV downloads.

kdm9.shinyapps.io/platemate/

#shiny #r #bioinformatics #molecularbiology #lab #plate

Last updated 1 year ago

Definitely the session we've all been waiting for- Integrating fossils and molecules to reconstruct the evolution of life in deep time!

#SMBE23 #smbe2023 #paleo #Evolution #molecularbiology

Last updated 1 year ago

I enjoyed presenting my poster at the Ferrara poster session. Lots of great conversations with interesting people and possible collaborations with people interested in of .

#SMBE23 #terrestrialization #Evolution #isopods #smbe2023 #Genomics #molecularbiology

Last updated 1 year ago

Ezgi AltΔ±nışık · @ezgi
219 followers · 33 posts · Server ecoevo.social

Hey, my first poll! Broadcasting to folks out there.

What is the biological technique called, where you isolate single cells, and grow out single cell founded populations from those single cells, by using a single dilution into multiple independent containers, where the presence or absence of a single cell in those containers (and hence, the outgrowth of a population) is governed by the Poisson equation?

(would help my manuscript writing)

#biology #cellbiology #microbiology #molecularbiology

Last updated 1 year ago

Daniel Prieto · @dprieto
25 followers · 212 posts · Server mastodon.uy
Christine Mordstein · @CMordstein
166 followers · 219 posts · Server genomic.social

🚨 We're expanding out Technologies team at Eleven Therapeutics! 🚨

πŸ‘‰ tinyurl.com/RNA11Tx πŸ‘ˆ

Come join us as a Senior Scientist and help develop the next generation of therapeutics! Our science couldn't be more cutting edge so don't miss this opportunity 😎

Please share!

#RNA #rnatherapeutics #jobalert #hiring #molecularbiology #methoddevelopment #Scientist #rnarocks

Last updated 1 year ago

TrangAston :verified: · @CastlTrAstonDrs
1325 followers · 2643 posts · Server med-mastodon.com

has seen no single Rx or combination proven to effectively halt disease progression, & the effect of the massive worldwide vaccination campaign is waning & the thread of near-future surges of this pandemic by subvariants. Pharmacological treatments that reduce the risk of progression from infected patients are imperfect, and their efficacy is restricted to the early intervention .

#IDMastodon #molecularbiology #drugdelivery #DrugDiscovery #COVID19pandemic #omicron #SarsCoV2

Last updated 1 year ago