Cerner Enviza and John Snow Labs are teaming up to develop an NLP algorithm that can take advantage of Cerner's #EHR data to look for #mentalhealth and behavioral side effects from the #asthma drug #montelukast

New @STAT:
https://www.statnews.com/2023/04/11/oracle-cerner-asthma-montelukast-artificial-intelligence-fda/

#NLP #AI #healthcare #healthtech

@mrbatsu

CCL11 (aka eotaxin-1) has been found to be elevated in ppl w/ Long Covid cognitive symptoms [1] & this could contribute to neuroinflammation.

Montelukast lowers CCL11 & research on repurposing for Alzheimer's is underway [2]. However, montelukast use has been linked to increased suicidal ideation.

Does anyone know why it would increase suicidal ideation?

1 - https://doi.org/10.1101/2022.01.07.475453
2 - https://clinicaltrials.gov/ct2/show/NCT03991988

#montelukast #neuroinflammation #CCL11

Don’t know if it’s the warm sunny weather after the abusively cold weather last week, or being off #Montelukast for approaching 48 hours but I’ve felt so much more clear headed and productive. So much of the last several years has felt like I’ve been in a fog.

If you take #Montelukast whether branded as #Singulair or generic for #Allergies or #Asthma it would be a good idea to read this bulletin from the #FDA and give consideration to whether it is worth continuing.

https://www.fda.gov/media/135840/download

#MentalHealth

Doing a bit of random research today and I found that the association between #LTRA drugs (typically used for #asthma and sometimes #allergies) and psychiatric side effects is more supported now than a few years ago. People taking #Singulair / #montelukast or #Accolate / #zafirlukast may be at higher risk for depression, suicidality, sleep disturbance, nightmares, and aggression (particularly in children). #LTRAs