Giuseppe Michieli · @GMIK69
105 followers · 2159 posts · Server mstdn.science''These results shed light on the mechanisms by which #SARS-CoV-2 evolves to develop #resistance to the current generation of #protease #inhibitors and provide the basis for the design of next-generation #Mpro inhibitors.''
#sars #resistance #protease #inhibitors #mpro
Giuseppe Michieli · @GMIK69
105 followers · 2158 posts · Server mstdn.scienceMolecular #mechanisms of #SARS-CoV-2 #resistance to #nirmatrelvir, Nature: https://www.nature.com/articles/s41586-023-06609-0 #research #antivirals #covid19 #drugs #mutations #mpro #protease
#mechanisms #sars #resistance #nirmatrelvir #research #antivirals #COVID19 #drugs #mutations #mpro #protease
Giuseppe Michieli · @GMIK69
54 followers · 968 posts · Server mstdn.scienceIdentification of #SARS-CoV-2 #Mpro #inhibitors containing P1’ 4-fluorobenzothiazole moiety highly active against SARS-CoV-2 https://www.nature.com/articles/s41467-023-36729-0