How does #RNA know where to go in the city of the #cell? Using cellular ZIP codes and postal carrier routes.
https://phys.org/news/2023-03-rna-city-cell-cellular-codes.html
How do select pre-#mRNAs escape 3’ end-processing inhibition by #DNAdamage?
Stephan Vagner and colleagues (Institut Curie) invoke rescue by a #cotranscriptional cleavage that allows subsequent #posttranscriptional #polyadenylation site processing in the nucleoplasm
Now published, previously a #RefereedPreprint via @ReviewCommons
#mrnas #dnadamage #cotranscriptional #posttranscriptional #polyadenylation #refereedpreprint
Development of a versatile method to synthesize functional #mRNAs with diverse 5' cap structures.
https://phys.org/news/2023-02-versatile-method-functional-mrnas-diverse.html
Long-standing mystery about #mRNAs resolved.
https://phys.org/news/2023-02-long-standing-mystery-mrnas.html
How does #bacterial #RNA #chaperone #Hfq regulate numerous different #mRNAs and processes?
#CryoEM by Tom Dendooven, Ben Luisi and collaborators shows assembly into distinct polymorphic #ribonucleoprotein complexes as basis
Translational regulation by Hfq–Crc assemblies emerges from polymorphic ribonucleoprotein folding
#bacterial #RNA #chaperone #hfq #mrnas #cryoem #ribonucleoprotein