Keith Dawson · @kdawson
247 followers · 569 posts · Server tldr.nettime.org

A preclinical trial in mice demonstrated that an adjuvant in an intranasal vaccine improved mucosal antibody and T cell responses against SARS-CoV-2. The adjuvant both boosted the mucosal immune response and disabled the virus directly. Early days. Remember: mice lie, monkeys exaggerate, and ferrets are not people.

U of M summary / interview
michiganmedicine.org/health-la

Paper
pubmed.ncbi.nlm.nih.gov/373860

#covid #vaccine #nasal #mucosal

Last updated 1 year ago

daniel · @travelhealthdoc
275 followers · 719 posts · Server med-mastodon.com

Promises and challenges of vaccines

"Several mucosal vaccines are currently being developed with the aim of inducing long-lasting protective immune responses at the mucosal sites where infection begins"

sciencedirect.com/science/arti

#mucosal #COVID19 #SarsCoV2

Last updated 2 years ago

Scientific Frontline · @sflorg
1055 followers · 2479 posts · Server mastodon.social

have developed an powder that could protect and airways from invasion by reinforcing the body’s own layer. The powder, called Spherical Inhalation for Enhanced Lung Defense, or

sflorg.com/2023/02/vi02092302.

#researchers #inhalable #lungs #viral #mucosal #hydrogel #shield #flu #COVID19 #virology #biology #engineering #medical #sflorg

Last updated 2 years ago

Lorraine · @Lorrrraaaaine
317 followers · 1243 posts · Server zeroes.ca

Supposing I were a
In order to max profits I’d want every woman, man & child to my

It probably wouldn’t be in my best interest to develop an ACTUAL that created immunity b/c that would mean I’d sell less ☹️
no, no, no;we can’t have that!

Cosmetics is INCREDIBLY jaw-droppingly b/c of something called
Imagine 300 million people addicted to constant 🤑

🖕🏼that

#sociopath #psychopath #pfizer #ceo #addicted #products #vaccine #mucosal #diabetes #hbp #antidepressants #pills #lucrative #replenishment #rx

Last updated 2 years ago

daniel · @travelhealthdoc
238 followers · 412 posts · Server med-mastodon.com

Good summary of the recent literature on immune in

Imprinting (a preferential memory response to parts of a pathogen that the immune system has seen before) may limit the effectiveness of variant-adapted booster vaccines.

New approaches including vaccines and novel adjuvants are being looked at.

However there is abundant evidence that the current to prevent hospitalisation and death.

nature.com/articles/d41586-023

#imprinting #COVID19 #mucosal #vaccineswork

Last updated 2 years ago

daniel · @travelhealthdoc
235 followers · 374 posts · Server med-mastodon.com

Rethinking against respiratory

"Because these viruses generally do not elicit complete and durable protective immunity by themselves, they have not to date been effectively controlled by licensed or experimental vaccines"

cell.com/cell-host-microbe/ful

#mucosal #vaccines #viruses

Last updated 2 years ago

Lorraine · @Lorrrraaaaine
295 followers · 1097 posts · Server zeroes.ca

@Covidcanada @kudra
🙏🏼🙏🏼🙏🏼🙏🏼🙏🏼
I’m the worst explainer; literally the worst even in regards to my own industry. Your explanation💯

Tend to believe or know things based on personal experience, which is quite unhelpful tbh

Had to “illegally” get & even convinced my💯ALWAYS-by-the-book-rule&law-abiding SO post my 2 shots,to get too

If studies came out proving some
protection, I’d believe it as something happens to my nose every time I’m exposed
Annual💉YES!

#iwantmynovavax #novavax #mucosal

Last updated 2 years ago

Justin Stewart · @thecrobe
563 followers · 283 posts · Server ecoevo.social
MBarral · @bn
11 followers · 48 posts · Server toot.community

Very nice Clinical Pipeline by @cyrilpedia COVID-19 fails to induce -immunity” at -Med doi: doi.org/10.1038/d41591-022-001

#IntranasalVaccines #Vaccine #mucosal #nature

Last updated 2 years ago

Jen Gommerman · @jengommerman
89 followers · 5 posts · Server qoto.org

I am an at the . I study how our immune system can influence our health, especially brain health. I love constructive discussions about science and how to make a better place for everyone. I love , , , and learning from my 2 sons. Oh and my 3 @Cats too.

#immunologist #universityoftoronto #cooking #gardening #singing #canoeing #mucosal #academia #introduction

Last updated 2 years ago


"Our findings indicate that respiratory delivery of Ad-vectored multivalent vaccine represents an effective next-generation COVID-19 strategy to induce all-around mucosal immunity against current and future VOC."

cell.com/cell/fulltext/S0092-8

#vaccine #mucosal #pandemic #COVID

Last updated 3 years ago