BCMA targeting CARTs in #MultipleMyeloma

"At a median follow-up of 15.9 months (range, 0.1 to 27.3), the median progression-free survival was not reached in the cilta-cel group and was 11.8 months in the standard-care group (hazard ratio, 0.26; 95% confidence interval [CI], 0.18 to 0.38; P<0.001). Progression-free survival at 12 months was 75.9% (95% CI, 69.4 to 81.1) in the cilta-cel group and 48.6% (95% CI, 41.5 to 55.3) in the standard-care group."

#Immunology #immunotherapy #cartcells

https://www.nejm.org/doi/full/10.1056/NEJMoa2303379?query=featured_home

Today science caught up with #MultipleMyeloma. A new treatment puts 90% of people with the cancer into remission!
https://www.jpost.com/health-and-wellness/article-744499

My jaw dropped open when I read this... I knew there was some progress but I didn't imagine it would be enough, or in time, to help me live my life without fear.

Today is a good day to celebrate the power of science, and appreciate the hard work being put in every day by researchers all over the world to help people living under cancer's shadow! 🎉🥳

3/3

For the past few months cooking and baking have been very utilitarian, in service to managing my #MultipleMyeloma and it’s treatments. Today a few days after leaving the hospital for my stem cell transplant I’m back with a big, old stack of lazy Sunday pancakes. Feels good.
#cooking #Baking

I just produced 23.3 million stem cells. I wouldn’t have imagined sitting in a chair for six hours for four days would be so exhausting. Very happy that part is done! #MultipleMyeloma

Access to innovative myeloma drugs remains ‘difficult’ in France https://www.euractiv.com/section/health-consumers/news/access-to-innovative-myeloma-drugs-remains-difficult-in-france/?utm_source=dlvr.it&utm_medium=mastodon #diagnosisandtreatment #multiplemyeloma #myeloma

Innovative therapies bring hope for German myeloma patients https://www.euractiv.com/section/health-consumers/news/innovative-therapies-bring-hope-for-german-myeloma-patients/?utm_source=dlvr.it&utm_medium=mastodon #cancer #multiplemyeloma #rarediseases

Abbott sales 18% fall due to anticipation of COVID testing sales declines —AstraZeneca confident new COVID antibody protects against known variants— J&J, Legend's Carvykti cut risk of progression or death by whopping 74% in earlier myeloma -- See more on our front page news http://bit.ly/w28kSd #abbottlabs #earnings #covid #covid19 #antibodies #astrazeneca #jnj #aacr #multiplemyeloma #pharma #pharmanews #biotech #biopharma #biotechnology #cafepharma

Ouchterlony double immuno diffusion! 😍
---
RT @Montse_JExpMed
In honor of the 30th annual Henry Kunkel Society Meeting on Protective and Pathogenic #Plasma Cells, here is a #JEMLegacy from Henry Kunkel himself on human #MultipleMyeloma proteins and antibodies. https://doi.org/10.1084/jem.101.1.85 Hope to see you around campus!
https://twitter.com/Montse_JExpMed/status/1646570443657338886

Anti-BCMA CART cells in relapsed and refractory multiple myeloma.

"At a median follow-up of 18.6 months, the median progression-free survival was 13.3 months in the ide-cel group, as compared with 4.4 months in the standard-regimen group (hazard ratio for disease progression or death, 0.49; 95% confidence interval, 0.38 to 0.65; P<0.001). A response occurred in 71% of the patients in the ide-cel group and in 42% of those in the standard-regimen group (P<0.001); a complete response occurred in 39% and 5%, respectively."

#Immunology #immunotherapy #CARTcells #MultipleMyeloma

https://www.nejm.org/doi/full/10.1056/NEJMoa2213614?query=featured_home

I'm about halfway through my #cancer treatments and while weekly stomach injections are not my favorite, you know what is? Sweet, sweet hemoglobin. I've been so anemic for so long I forgot oxygenated blood feels like. 10/10 I highly recommend it. #MultipleMyeloma

Our @HarmonynetEU@twitter.com project is using #BigData to improve the care of people with blood #cancer, eg last year they identified a better way of assessing the prognosis of people newly diagnosed with #MultipleMyeloma
Read more: https://bit.ly/3dt1xyw
#WorldCancerDay

Off-the-shelf CARTs

"Nevertheless, generation of autologous CAR T cell products is extremely time consuming and costly, prompting researchers to explore alternative strategies to overcome these limitations. In this issue of Nature Medicine, Mailankody et al.4 report results of part A of the phase 1 UNIVERSAL clinical trial, which evaluated ALLO-715, an allogeneic off-the-shelf anti-BCMA CAR T cell product."

#CARTcells #Immunology #Immunotherapy #NatureMedicine #MultipleMyeloma #Hematology

https://www.nature.com/articles/s41591-022-02195-2

RT @NCIsysbio
Dr. Nicholas Graham, @USCSysBio_Lab, et al. @USCViterbi #NCICSBC are investigating #ChimericAntigenReceptor (CAR)-mediated Natural Killer cell signaling to inform the design of #immunotherapies for #multiplemyeloma. https://reporter.nih.gov/search/xb8Mbt37xEO5MhSqAhNPhQ/project-details/10557760

#MultipleMyeloma patients may soon be able to look forward to better-targeted treatments thanks to IMI project @HarmonynetEU@twitter.com which proposed a new, more accurate way of assessing the prognosis of patients
http://bit.ly/3dt1xyw

Researchers discovered a mechanism which provides indications of when and why cells become aggressive and cause #MultipleMyeloma. These findings could help with future #pharmaceutical development: http://go.tum.de/450805

#PlasmaCells #CancerResearch
📷toeytoey2530/iStock

Please watch out for us with invisible illnesses.

Did you know that in Multiple Myeloma patients a study was conducted that showed the COVID vaccine was only effective about 50% of the time?

That means each time a Multiple Myeloma patient gets the shot, it is like a chance between the real shot or water.

MM is a blood cancer that can't be cured but can be survivable with the help of others.

#multiplemyeloma #COVID #disability

#introduction I just joined last night. I figured I would intro myself.

Greygendered & 51-year-old & disabled.

I have epilepsy, diabetes, multiple myeloma & hx of stroke.

I love reading & playing video games.

#disability #multiplemyeloma #epilepsy #greygender #enby

GSK to pull blood cancer drug from US market after study failure — Health tech companies weigh funding options amid weak IPO market —Cancer drugmaker Plexxikon gets new life as Opna Bio -- See more on our front page news http://bit.ly/w28kSd #gsk #multiplemyeloma #medtech #funding #ipos #cancer #rebranding #pharma #pharmanews #biotech #biotechnology #biopharma #cafepharma

MULTIPLE MYELOMA & LEUKEMIA - AN IN-DEPTH LOOK

Blood cancer, also known as Leukemia, is one of the most common cancers in children, but also affects many adults. What causes it? Which are the symptoms you must look out for? Are there different types of leukemia and what are the differences between them? How can you diagnose it?
Find out in our newest video, where we answer these questions and more:
https://www.bitchute.com/video/aYehnlKraVL5/
https://odysee.com/@LyraNara:3/Myeloma-and-Leukemia:f

For the personal holistic care you need and deserve contact us at:
https://christine.doctor

Get the most powerful holistic tools here:
https://vibrant-body.net/

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#health #holistichealing #holistichealth #leukemia #bloodcancer #multiplemyeloma #acuteleukemia #chronicleukemia #lymphocyticleukemia #biologicalconflicts
#myeloma #cancer