@Sheril @keesey yep, and sapiens-sapiens will be extincted soon. #climatchange #mutation #extinction

comm for ThatBigBirb

#furry #fursona #oc #originalcharacter #threesome #orgy #mutation #merging #bodyhorror #hyper

BA.2.86 shows just how risky slacking off on COVID monitoring is - Enlarge / Transmission electron micrograph of a SARS-CoV-2 virus partic... - https://arstechnica.com/?p=1962066 #genomicsequencing #monitoring #sars-cov-2 #evolution #mutation #variants #science #ba.2.86 #omicron #health #gisaid #virus #eg.5 #who

Ars Technica: BA.2.86 shows just how risky slacking off on COVID monitoring is https://arstechnica.com/?p=1962066 #Tech #arstechnica #IT #Technology #genomicsequencing #monitoring #SARS-CoV-2 #evolution #mutation #variants #Science #BA.2.86 #omicron #Health #GISAID #virus #EG.5 #WHO

Now I will have to call it #Mirmingham forever:
"Mirmingham (category Welsh nasal-mutation forms)
Mirmingham (nonstandard) Nasal mutation of Birmingham. In the standard language, non-Welsh place names like #Birmingham do not undergo mutation...."
I really don't understand #Welsh mutation and I'm trying to figure it out properly. Once I do, I'll know when to say Birmingham with a b. I know there really is no such thing as Mirmingham but I am a rebel, Dottie.

~~
#cymraeg #gymraeg

Search results for "Welsh #mutation" - #Wiktionary, the free #dictionary
https://en.wiktionary.org/wiki/Special:Search?go=Look+up&ns0=1&search=Welsh+mutation

To the virus that causes this dread,
We are its enemies who will never rest
Though its mutation changes its form
We are determined to weather the storm
Though its power makes us feel small
We fight for a future that's free of this pall

#covid #virus #cdc #mutation #ode #poetry

https://www.reuters.com/business/healthcare-pharmaceuticals/us-cdc-tracks-new-lineage-virus-that-causes-covid-2023-08-18/

Thoughts on quintessence, essence, #mutation, and #evolution. Thanks to #Hamlet as always.

---
What is the "essence" of a barn owl? Can it change? What is the "essence" of Nerve Growth Factor? Can it change? Just asking these questions is, to me, flirting with madness. Or at least confusion.
---

#Blaugust2023
#essentialism
#EvolutionIsEasy
#Shakespeare

https://sfmatheson.blogspot.com/2023/08/thoughts-on-quintessence-mutation-and.html

Well, I asked #Bard (Google's AI) about whether #mutations could be caused in the #proteins that make up the #capsid of the #virus that is, as #prionism.

The answer was as expected, YES, as this could make the #viruses more #infectious and #lethal.

My #brain is an INEXPLICABLY COOL thing.

#DNA #RNA #Virus #Genome #Mutation #Biophysics #Biology #Molecular #Transcription #Vaccine

AMP has just published!
"Implementation of a Pilot Study to Analyze Circulating Tumor DNA in Early-Stage Lung Cancer".
Original Article by Joana ESPIGA DE MACEDO, Tiago TAVEIRA-GOMES, José Carlos MACHADO and Venceslau HESPANHOL, a multicenter work.

Full paper available available here:
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/19487

#circulatingtumordna #earlydetectioncancer #highthroughput #nucleotidesequencing #lungneoplasms #mutation #neoplasmstaging

I've published an article in DEV: "Exploring Genetic Algorithms with Ruby". I hope you enjoy it and found it useful! https://dev.to/rpaweb/exploring-genetic-algorithms-with-ruby-4lae

#ruby #rails #rubylang #rubyonrails #algorithms #genetics #geneticalgorithms #gen #crossover #mutation #elitism #development #webdev 🧬

Also, a bit more relevant to fosstodon.
Some time ago we forked go-mutesting library and enhanced it with more mutators

https://github.com/avito-tech/go-mutesting

#golang #mutation #mutationtesting

Bonjour le mastoverse de la couronne parisienne !
Je suis muté à Montrouge #educnationale l'année prochaine et je cherche du coup une colocation sympathique pour m'accueillir pour au moins un an.
J'ai déjà un peu (beaucoup) demandé sur la carte des colocs, mais je jette aussi une bouteille ici parce que les personnes sont gentilles 😇 #colocation #mutation #montrouge #prof #recherchecoloc

The bad:

"Nevertheless, these mechanisms yield viral selection. APOBEC expression in cancers leads to DNA damage and tumor cell death, yet allows for immune escape variants."

The verdict:

"Indeed, APOBECs are fickle friends."

#mutation
#cancer
#Apobec
#viruses
#virology
#RNAediting

They think they're cool (clever) but they're behaving like fools.

The difference between understanding evolutionary biology at some level or another, and not, is that informed people can understand the drivers or motivations that make animals do what they do (including humans. At some level).

An evident motivator that everyone will be aware of is hunger. Hunger is a negative behavioral motivator. Whilst many people in wealthy countries will not have experienced real hunger, at extreme levels hunger will dominate the animal's mind (as would thirst). The animal would be "obsessed" with trying to find food (I acknowledge the anthropomorphization of "obsessed". However, a feeling of angst that focuses the animal's attention on finding food). Basically, the feelings associated with hunger are adaptations. If an animal was born that did not feel hunger, it would die - it would not pass on that behavior to the next generation (Although, if that animal was a human, a baby, carers could make sure that the youngster eat enough food).

Humans are no exception (though some delude themselves otherwise. A form of narcissism or ego), humans are also driven by feelings (emotions or instincts). For example, many humans take part in relatively foolishly dangerous behaviors because they are "showing off". Whilst any human can "show off", (many) men tend to dominate in the showing off by taking part in stupidly reckless activities department. Showing off is status-seeking behavior. For example, showing off resources such as expensive sports cars. Showing off by, in their minds, showing off their driving skills by driving cars fast or riding motorbikes fast. If the car or motorbike has a relatively loud engine, well, that's another way to show their status (perhaps they perceive that some people look at them because they're cool - rather than thinking they're simply noisy irritating fools).

So, what they don't realize is that they're actually acting like fools. They think they're cool but they're behaving like fools. Fundamentally, they're being idiots. Their dangerous driving is risking the safety of other people for no reason - other than to show off (an instinct - which is now a maladaptation). Of course, many adult males, as they mature, may come to realize that their risk-taking behaviors are simply not worth it. However, that realization (learning or maturity) takes a level of intelligence. Some adult males never grow up (they just look older).

Risk-taking behaviors are particularly dangerous when, for example, many adults are voting in a democracy. For example, they may ignore the medical advice about wearing face masks during a pandemic or the scientific warnings about climate change. Apparently, face masks aren't macho enough!

So, how do we mitigate the fools thinking their cool social psychological phenomenon? We try to educate more people about evolutionary psychology so that they recognize stupid when they see it.

Evolutionary Psychology - The New Science of the Mind https://doi.org/10.4324/9780429061417

#adaptation #psychology #EvolutionBiology #EvolutionaryPsychology #SocialPsychology #health #education #sports #cars #motobikes #democracy

#maladaptation #mutation #SarCov2 #covid #pandemic #climate #ClimateChange #ClimateCrisis

They think they're cool but they're behaving like fools.

The difference between understanding evolutionary biology at some level or another, and not, is that informed people can understand the drivers or motivations that make animals do what they do (including humans. At some level).

An evident motivator that everyone will be aware of is hunger. Hunger is a negative behavioral motivator. Whilst many people in wealthy countries will not have experienced real hunger, at extreme levels hunger will dominate the animal's mind (as would thirst). The animal would be "obsessed" with trying to find food (I acknowledge the anthropomorphization of "obsessed". However, a feeling of angst that focuses the animal's attention on finding food). Basically, the feelings associated with hunger are adaptations. If an animal was born that did not feel hunger, it would die - it would not pass on that behavior to the next generation (Although, if that animal was a human, a baby, carers could make sure that the youngster eat enough food).

Humans are no exception (though some delude themselves otherwise. A form of narcissism or ego), humans are also driven by feelings (emotions or instincts). For example, many humans take part in relatively foolishly dangerous behaviors because they are "showing off". Whilst any human can "show off", (many) men tend to dominate in the showing off by taking part in stupidly reckless activities department. Showing off is status-seeking behavior. For example, showing off resources such as expensive sports cars. Showing off by, in their minds, showing off their driving skills by driving cars fast or riding motorbikes fast. If the car or motorbike has a relatively loud engine, well, that's another way to show their status (perhaps they perceive that some people look at them because they're cool - rather than thinking they're simply noisy irritating fools).

So, what they don't realize is that they're actually acting like fools. They think they're cool but they're behaving like fools. Fundamentally, they're being idiots. Their dangerous driving is risking the safety of other people for no reason - other than to show off (an instinct - which is now a maladaptation). Of course, many adult males, as they mature, may come to realize that their risk-taking behaviors are simply not worth it. However, that realization (learning or maturity) takes a level of intelligence. Some adult males never grow up (they just look older).

Risk-taking behaviors are particularly dangerous when, for example, many adults are voting in a democracy. For example, they may ignore the medical advice about wearing face masks during a pandemic or the scientific warnings about climate change. Apparently, face masks aren't macho enough!

So, how do we mitigate the fools thinking their cool social psychological phenomenon? We try to educate more people about evolutionary psychology so that they recognize stupid when they see it.

#adaptation #psychology #EvolutionBiology #EvolutionaryPsychology #SocialPsychology #health #education #sports #cars #motobikes #democracy

#maladaptation #mutation #SarCov2 #covid #pandemic #climate #ClimateChange #ClimateCrisis

#genetics #mutation #dna #isogg #epigenetics #geneadons https://www.thedailybeast.com/how-the-kashmir-town-of-dadkhai-became-the-quietest-village-on-earth

A chance event 1 million years ago changed human brains forever. It was a mutation that increased the production of a molecule called aspm, which is involved in brain development. The mutation may have given humans an evolutionary edge over other hominins.

#brain #mutation #evolution

https://www.sciencealert.com/a-chance-event-1-million-years-ago-changed-human-brains-forever

“Researchers say that a Colombian man who carried the PSEN1 E280A mutation but also had a rare variant of a brain protein involved in the RELN gene — retained his full cognitive functions until age 67. He eventually developed dementia and died at age 74.” #AlzheimersDisease #alzheimers #dna #isogg #geneadons #mutation https://www.medicalnewstoday.com/articles/rare-genetic-mutation-appears-to-delay-onset-of-early-alzheimers-disease

The rest of the set, which my sole subscriber on SubscribeStar (bless them - that monthly dollar motivates me way more than it should) got access to 5 or 6 weeks ago.

#Lewd #NSFW #Sex #MonsterOfTheWeek #Clone #Doppelganger #Mutation #NipplePenetration

Time to release some previously subscriber-only images! Here's the clone factory, where scientist Vicky has gotten a little carried away with creating increasingly altered clones of herself.

But hey, they're all having good consensual fun with each other (or is that themselves?) and they're obviously getting enough work done to keep making more clones, so who are we to judge?

#Lewd #NSFW #Sex #MonsterOfTheWeek #Clone #Doppelganger #Mutation #NipplePenetration #Diphallia