Daniel MacPhee 🥼🔬🧬🧫🇨🇦 · @dmacphee
628 followers · 3938 posts · Server mas.toMyc and the placenta.
“These data reveal Myc is essential for polyploidy to support normal placental development, thereby preventing premature senescence. “
#placenta #Myc #Trophoblast #senescence #reproduction #DevBio #Science
https://journals.biologists.com/dev/article/150/11/dev201581/316006/Myc-promotes-polyploidy-in-murine-trophoblast
#science #devbio #reproduction #senescence #trophoblast #myc #placenta
The EMBO Journal · @embojournal
440 followers · 171 posts · Server sciencemastodon.com
#YAP/#BRD4-controlled ROR1 promotes tumor-initiating cells and #hyperproliferation in #pancreaticcancer
Masaya Yamazaki et al show that #ROR1 marks an aggressive partial #EMT cell cluster and enhances #PDAC proliferation via c-#Myc/#E2F/#AURKB signaling
#yap #hyperproliferation #pancreaticcancer #ror1 #EMT #pdac #myc
Scientific Frontline · @sflorg
669 followers · 1678 posts · Server mastodon.social
#MYC #genes and their #proteins play a central role in the emergence and development of almost all #cancers. They drive the uncontrolled growth and altered metabolism of tumor cells. And they help tumors hide from the #immune system.
#Biology #Pharmaceutical #sflorg
https://www.sflorg.com/2022/11/bio11252202.html
#myc #genes #proteins #cancers #immune #biology #pharmaceutical #sflorg