onisillos · @onisillos
741 followers · 351 posts · Server mstdn.science

I only just hear about as potential therapeutics and already learn about resistance mechanisms.

Therapeutically useful mycobacteriophages BPs and Muddy require trehalose polyphleates

nature.com/articles/s41564-023

#mycobacteriophages #AMR #phages #IDMastodon #infectiousdiseases #mycobacterium

Last updated 1 year ago

onisillos · @onisillos
565 followers · 1141 posts · Server scicomm.xyz

New research article in The Lancet Microbe>

Effect of compensatory evolution in the emergence and transmission of -resistant in Cape Town, : a genomic epidemiology study

thelancet.com/journals/lanmic/

#AMR #tb #southafrica #tuberculosis #mycobacterium #rifampicin

Last updated 1 year ago

Fco Javier Casas Ciria · @cientounero
316 followers · 617 posts · Server mstdn.science

En pacientes diagnosticado de infecci贸n por del Complejo y relacionado con ganado caprino, matadero o toma de leche no pasteurizada hay que intentar descartar por secuenciaci贸n

Eurosurveillance | A One Health approach revealed the long-term role of Mycobacterium caprae as the hidden cause of human tuberculosis in a region of Spain, 2003 to 2022 eurosurveillance.org/content/1

#micobacteria #Tuberculosis #mycobacterium #caprae #mycobacteriumcaprae

Last updated 2 years ago

onisillos · @onisillos
551 followers · 1022 posts · Server scicomm.xyz
yeti · @yeti
79 followers · 160 posts · Server emacs.ch
The EMBO Journal · @embojournal
424 followers · 131 posts · Server sciencemastodon.com

Uptake-independent killing of macrophages by extracellular aggregates

Chiara Toniolo et al show that Mtb aggregates evade by inducing via a mechanism involving its type VII secretion system ESX-1 and surface lipid PDIM

embopress.org/doi/10.15252/emb

#mycobacterium #tuberculosis #phagocytosis #macrophage #pyroptosis

Last updated 2 years ago

CellBioNews · @cellbionews
34 followers · 733 posts · Server scientificnetwork.de

Newly discovered that turns air into electricity, providing a new clean source of energy.

phys.org/news/2023-03-newly-en

#enzyme #bacteria #hydrogen #biofuels #mycobacterium #huc

Last updated 2 years ago

onisillos · @onisillos
538 followers · 917 posts · Server scicomm.xyz

New review article in The Lancet Infectious Diseases>

Clinical implications of molecular drug resistance testing for : a 2023 TBnet/RESIST-TB consensus statement

thelancet.com/journals/laninf/

#AMR #tb #tuberculosis #mycobacterium

Last updated 2 years ago

Gabriele Pollara · @gpollara
720 followers · 1669 posts · Server med-mastodon.com

@cyrilpedia
Yes, and that disconnect with IFNa/b responses also important to highlight.

The role of type I IFN in TB still to be worked out. They're there, but doing what?!

#infetionimmunity #infectiousdisease #mycobacterium #tuberculosis #immunology

Last updated 2 years ago

Thiago Carvalho · @cyrilpedia
1532 followers · 4877 posts · Server qoto.org

"Thus, studies of MSMD (Mendelian susceptibility to mycobacterial disease ) have revealed that human antimycobacterial immunity is a genetically controlled quantitative trait: the lower the level of IFN-纬 activity, the more severe the disease and the higher its penetrance"

cell.com/cell/fulltext/S0092-8

#InfetionImmunity #infectiousdisease #mycobacterium #tuberculosis #immunology

Last updated 2 years ago

CellBioNews · @cellbionews
24 followers · 488 posts · Server scientificnetwork.de
onisillos · @onisillos
528 followers · 795 posts · Server scicomm.xyz

The February issue of The Lancet Microbe is now online:

thelancet.com/journals/lanmic/

The journal is , so you are free to explore all of the content, but these hashtags offer a flavour:

#oa #hiv #loiasis #loaloa #AMR #dst #wgs #tb #tuberculosis #mycobacterium #staphylococcus #Bacillus #probiotic #openaccess

Last updated 2 years ago

onisillos · @onisillos
525 followers · 765 posts · Server scicomm.xyz

New correspondence in The Lancet Microbe>

Phenotypic instability of strains harbouring clinically prevalent drug-resistant mutations

thelancet.com/journals/lanmic/

#AMR #tb #tuberculosis #mycobacterium

Last updated 2 years ago

Boris Tefsen · @boristefsen
25 followers · 67 posts · Server mas.to
Lance Taylor 馃捑 · @lancetay
242 followers · 1487 posts · Server home.social

So, I found out what nearly killed me today from the doctor. Starting treatment today for the next 6 - 8 weeks.

en.wikipedia.org/wiki/Mycobact

#mycobacterium #fishkeeping #aquarium

Last updated 2 years ago

onisillos · @onisillos
461 followers · 556 posts · Server scicomm.xyz

New research article in The Lancet Microbe> Evaluation of sequencing for drug susceptibility testing and outbreak investigation: a genomic analysis thelancet.com/journals/lanmic/

#AMR #tb #tuberculosis #mycobacterium #nanopore

Last updated 2 years ago

Fco Javier Casas Ciria · @cientounero
315 followers · 597 posts · Server mstdn.science

Fenotipo de resilencia antibi贸tica de tuberculosis por mutaci贸n en gen _resR_ (regulador de resilencia) que origina acortamiento del efecto post-antibi贸tico

Antibiotic resilience phenotype of tuberculosis due to mutation in the _resR_ gene (resilience regulator) that causes shortening of the post-antibiotic effect

science.org/doi/10.1126/scienc

#mycobacterium

Last updated 2 years ago

Thiago Carvalho · @cyrilpedia
935 followers · 1562 posts · Server qoto.org

My latest column for is a look at early human results of a new class of for

The mechanism of action is essentially to clog the 's tRNA synthetase - the result of two decades of research on boron-based compounds.


nature.com/articles/d41591-022

#tuberculosis #mycobacterium #IDMastodon #naturemedicine #antibiotics #drugdevelopment #antibioticresistance

Last updated 2 years ago

PLOS Biology · @PLOSBiology
3177 followers · 198 posts · Server fediscience.org

How does transport nutrients across its outer membrane? Study shows that a member of the large PE/PPE protein family imports , suggesting family-wide role as atypical nutrient transporters plos.io/3ASpg3z

#plosbiology #TB #bacterial #calcium #tuberculosis #mycobacterium

Last updated 2 years ago

PLOS Biology · @PLOSBiology
3170 followers · 194 posts · Server fediscience.org

How does transport nutrients across its outer membrane? Study shows that a member of the large PE/PPE protein family imports , suggesting family-wide role as atypical nutrient transporters plos.io/3ASpg3z

#plosbiology #TB #bacterial #calcium #tuberculosis #mycobacterium

Last updated 2 years ago