A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology https://plos.io/3YHNvdR
#plosbiology #thalamocortical #gabaergic #myelination #plasticity
A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology https://plos.io/3YHNvdR
#plosbiology #thalamocortical #gabaergic #myelination #plasticity
A network of #plasticity mechanisms: subcortical microstructural (#myelination) plasticity & cortical neurochemical (#GABAergic) plasticity interact via #thalamocortical connectivity to support optimized perceptual decisions @CambridgeABL #PLOSBiology https://plos.io/3YHNvdR
#plosbiology #thalamocortical #gabaergic #myelination #plasticity
Anthea Weng, Erik Rabin & co show that alpha-T-catenin is expressed in peripheral #nerves as a constituent of Schwann cell adherens junctions:
“We show that a cell connecting gene that is found in nerves and their surrounding supporting cells may play key roles in the basis of many diseases.”
We interviewed Anthea and Erik to find out more about their research:
#Catenin #Myelination #Neuroglia #Neurons #Science #BiologyOpen #Biology
#nerves #catenin #myelination #neuroglia #neurons #Science #biologyopen #biology
RT @manoliskellis@twitter.com
This week in @Nature@twitter.com we present our #SingleCell dissection of #ApoE4, the strongest genetic variant for #Alzheimers.
ApoE4 impairs #cholesterol #transport, leading to #oligodendrocyte ER accumulation, decreased #myelination.
Restoring transport restores mouse cognition.
#Hope #AD
🐦🔗: https://twitter.com/manoliskellis/status/1594656572227084294
#SingleCell #apoe4 #alzheimers #cholesterol #transport #oligodendrocyte #myelination #hope #ad
RT @manoliskellis@twitter.com
This week in @Nature@twitter.com we present our #SingleCell dissection of #ApoE4, the strongest genetic variant for #Alzheimers.
ApoE4 impairs #cholesterol #transport, leading to #oligodendrocyte ER accumulation, decreased #myelination.
Restoring transport restores mouse cognition.
#Hope #AD
🐦🔗: https://twitter.com/manoliskellis/status/1594656572227084294
#singlecell #apoe4 #alzheimers #cholesterol #transport #oligodendrocyte #myelination #hope #ad
RT @manoliskellis@twitter.com
This week in @Nature@twitter.com we present our #SingleCell dissection of #ApoE4, the strongest genetic variant for #Alzheimers.
ApoE4 impairs #cholesterol #transport, leading to #oligodendrocyte ER accumulation, decreased #myelination.
Restoring transport restores mouse cognition.
#Hope #AD
🐦🔗: https://twitter.com/manoliskellis/status/1594656572227084294
#singlecell #apoe4 #alzheimers #cholesterol #transport #oligodendrocyte #myelination #hope #ad
RT @manoliskellis@twitter.com
This week in @Nature@twitter.com we present our #SingleCell dissection of #ApoE4, the strongest genetic variant for #Alzheimers.
ApoE4 impairs #cholesterol #transport, leading to #oligodendrocyte ER accumulation, decreased #myelination.
Restoring transport restores mouse cognition.
#Hope #AD
🐦🔗: https://twitter.com/manoliskellis/status/1594656572227084294
#singlecell #APOE4 #alzheimers #cholesterol #transport #oligodendrocyte #myelination #hope #ad
#Introduction Hi! I am Sara and I’m still trying to get used to Mastodon.
I am a #neuroscientist and an #activist.
I am intrested in #inhibitory networks, learning and #memory , slice and in vivo #ephys and #myelination
I fight for #queerliberation and #transrights , against #racism and for a #freepalestine.
My favorite statement: The personal is political.
#freepalestine #racism #transrights #queerliberation #myelination #ephys #memory #inhibitory #activist #neuroscientist #introduction
Did you know that #myelination of neuronal axons by #oligodendrocytes in our #brain is a plastic process in which #myelin structure (white matter) can change in response to neuronal activity?
Here is a very interesting review article by Juliet Knowles and colleagues at Stanford University:
Adaptive and maladaptive myelination in health and disease
#OpenAccess article in Nature Reviews #Neurology: https://www.nature.com/articles/s41582-022-00737-3
#myelination #oligodendrocytes #brain #myelin #openaccess #neurology #neuroscience #psychiatricdiseases