Coronary #EndothelialCells want WT1 as well

A Research Highlight showcasing new work from Marina Ramiro-Pareta, Ofelia Martínez-Estrada & colleagues

https://journals.biologists.com/dev/article/150/6/e150_e0603/299060/Coronary-endothelial-cells-want-WT1-as-well

Read the full #OpenAccess Research Article, 'Endothelial deletion of #Wt1 disrupts coronary #angiogenesis and #myocardium development', here:
https://journals.biologists.com/dev/article/150/6/dev201147/297331/Endothelial-deletion-of-Wt1-disrupts-coronary

We interviewed the authors, Marina Ramiro-Pareta & Ofelia Martínez-Estrada for our 'The people behind the papers' series:
https://journals.biologists.com/dev/article/150/6/dev201740/297330/The-people-behind-the-papers-Marina-Ramiro-Pareta

#devbio

Adenosine is a molecule that plays a role in many different biological processes. It is involved in the #hyperaemic response, which is when the blood flow to the #myocardium (heart muscle) increases in response to #hypoxia or ischemia (lack of oxygen). Adenosine is also involved in #bone remodelling, where it can activate certain receptors to either increase or decrease the development of #osteoclasts (cells that break down bone).