Keisuke Shigeta et al (Keio University School of Medicine) analyze #metabolic alterations leading to #chemoresistance in #urothelial cancer #bladdercancer: #IDH2 gain-of-function independent of #mutation is responsible for #HIF1α-dependent production of respective #gemcitabine and #CDDP competitors #dCTP and #NADPH
#metabolic #chemoresistance #urothelial #bladdercancer #idh2 #Mutation #hif1α #gemcitabine #cddp #dctp #nadph
Latest curated articles👇🏽
📰#Structure of the core human #NADPH oxidase NOX2 (in 📷)
📰#Epigenetic age in #singlecells.
🦛The #Hippo pathway links #adipocyte plasticity to #adiposetissue fibrosis.
🔗http://biomed.news/bims-nimamd/2022-10-16
🙏🏽Thx @biomednews@twitter.com
#structure #nadph #epigenetic #singlecells #hippo #adipocyte #adiposetissue