Development of a novel therapeutic modality termed bispecific complement engager (BiCE) that directs complement activity to the surface of HIV-1 envelope-expressing cells, resulting in complement-mediated elimination of these cells.

#HIV #nanobody

By M.L. Pedersen, M. Tolstrup & colleagues at Aarhus University

🗞️ https://doi.org/10.15252/emmm.202216422

The latest results from my postdoc at the Kulathu lab are now on BioRxiv!
🔗 http://bit.ly/branched-K48-K63-Ub 🔗

#ubiquitin #nanobody #DUBs #p97

Amazing team effort - thanks to everyone involved!🥳

Die Münchner von Plectonic Biotech wollen #Krebszellen mit #DNAOrigami an den Kragen. Zuerst mussten die „tollkühnen Physiker“ aber lernen, mit #Zellen zu arbeiten. Wie das lief und was dabei herauskam, erzählt Tobias Ludwig: 👉 https://www.laborjournal.de/editorials/2665.php

#biotech #startup #nanobody

Nice and concise #review about the different #methods to increase effective molecular weight of #proteins <100 ​kDa through target protein binding or target protein fusion (#nanobody and symmetric #scaffolds) enabling structure determination with #cryo-EM @strucbio

https://www.sciencedirect.com/science/article/pii/S2665928X22000290