Was just reading this nice commentary piece from Ed Grow published at #NatureGenetics and was surprised/thrilled to see a reference to our BioRxiv study Meng et al.
https://www.nature.com/articles/s41588-022-01111-1
https://doi.org/10.1101/2022.03.31.486614

'Herein, we demonstrate that tumor aneuploidy provides independent prognostic value among patients with lower TMB (<80th percentile) tumors treated with immunotherapy. A higher aneuploidy score is associated with poor prognosis following immunotherapy among tumors with low TMB, but not those with high TMB.'

#Immunology #Immunotherapy #NatureGenetics

https://www.nature.com/articles/s41588-022-01235-4

I also work on the #genomes of various cultivated #plants, such as the #lychee - we published its #genome earlier this year in #NatureGenetics - "Two divergent haplotypes from a highly heterozygous lychee genome suggest independent domestication events for early and late-maturing cultivars" - https://www.nature.com/articles/s41588-021-00971-3 #EvolutionaryBiology #botany #bioinformatics #DNA