Neuroblastoma is a #cancer in children that is sometimes benign, but can also be very aggressive. Researchers from #CharitéBerlin & @MDC_Berlin now show: Specific patterns of DNA alterations in #neuroblastoma cells reflect the different aggressiveness of this pediatric #tumor. The results could provide a starting point for a more targeted approach to treatment.
https://www.charite.de/en/research/paper_spotlight/2023/new_findings_on_the_biological_processes_behind_neuroblastoma_risk_differences/

#Medicine #Research #CharitéPaper #CharitéOncology #ScienceMastodon #MedMastodon

A new piece of the puzzle on how #neuroblastoma – a #cancer affecting children – develops: A #CharitéBerlin study shows that the #tumor forms RNA rings that contribute to the growth of cancer cells. In the future, RNA therapeutics could target these rings.

👉 https://www.charite.de/en/research/engl_neues_aus_der_forschung/2023/new_findings_on_the_role_of_rna_rings_in_neuroblastoma/

#Medicine #ScienceMastodon #Science #RNA #CharitéPaper #CharitéOncology

Efficacia delle cellule CAR-T sui neuroblastomi. Le cellule CAR T sono efficaci contro i neuroblastomi, tumori solidi che colpiscono i bambini. Per la prima volta una terapia genica con cellule CAR T si è dimostrata in grado di trattare con successo i neuroblastomi, tumori solidi che possono manifestarsi in età pediatrica.
#celluleCART #ChimericAntigenReceptor #neuroblastoma #tumorecervello

https://scienzamagia.eu/medicina-e-benessere/efficacia-delle-cellule-car-t-sui-neuroblastomi/

Referenced link: https://medicalxpress.com/news/2023-04-lorlatinib-safe-effective-patients-alk-driven.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-04-lorlatinib-safe-effective-patients-alk-driven.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1642919158080757761#m

RT by @physorg_com: Lorlatinib found to be safe and effective for #patients with ALK-driven relapsed/refractory high-risk #neuroblastoma @NatureMedicine https://medicalxpress.com/news/2023-04-lorlatinib-safe-effective-patients-alk-driven.html

Referenced link: https://medicalxpress.com/news/2023-03-neuroblastoma-outcomes-molecular-evolution.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2023-03-neuroblastoma-outcomes-molecular-evolution.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/medical_xpress/status/1641107959466934277#m

RT by @physorg_com: Predicting #neuroblastoma outcomes with molecular evolution @NatureGenet https://www.nature.com/articles/s41588-023-01332-y https://medicalxpress.com/news/2023-03-neuroblastoma-outcomes-molecular-evolution.html

Batteri ibridi con materiali sintetici per la cura del cancro. I batteri cyborg che sopravvivono in un ambiente ostile. Potrebbero combattere tumori e risolvere problemi ambientali. Ottenute in laboratorio le prime cellule ‘cyborg’: sono batteri ibridi, a metà tra naturale e artificiale, cioè cellule in cui sono stati introdotti materiali sintetici.
#battericybord #batteriibridi #cellulecyborg #cureanticancro #microbiomaintestinale #neuroblastoma

https://scienzamagia.eu/ambiente-territorio/batteri-ibridi-con-materiali-sintetici-per-la-cura-del-cancro/

RT @RareRevolutionM@twitter.com

From @BBCNews@twitter.com: "Telford girl with #RareCancer sees good results in trial".

"A six-year-old girl has been the first in the UK to trial a new treatment in her continuing battle against a rare form of #Cancer called #Neuroblastoma"

Read the article here: http://bit.ly/3XfrD9m

🐦🔗: https://twitter.com/RareRevolutionM/status/1614593458647302147

RT @CapitiniMD@twitter.com

Congrats to the Slukvin Lab @UWiscPathology@twitter.com @uwsmph@twitter.com @UWSCRMC@twitter.com @UWCarbone@twitter.com for generating iPSC-derived GD2 #CARmacrophages active against #melanoma and #neuroblastoma @stemcellreports@twitter.com A nice potential "off-the-shelf" cell therapy for pediatric solid tumors https://www.cell.com/stem-cell-reports/fulltext/S2213-6711(22)00604-X

🐦🔗: https://twitter.com/CapitiniMD/status/1613620964062908417

My family has held plenty of Lemonade Stands to support Alex's Lemonade Stand Foundation. So many in fact that we built our own stand with their plans: https://www.alexslemonade.org/files/downloads/resource_stand_construction.pdf
And as a side note, my son had the same cancer as Alex called #Neuroblastoma and he even does speaking engagements for #ALSF

Latest work from our lab examining the interface between tumour initiation and embryonic cell fate decisions: a great collaboration with Florian Halbritter, spearheaded by Ingrid Saldana-Guerrero and Luis Montano-Gutierrez (all Mastodon-less, I think) #devbiol #Devbiol #stemcell #cancer #neuroblastoma #neuralcrest
https://www.biorxiv.org/content/10.1101/2022.11.21.515753v1

Latest work from our lab examining the interface between tumour initiation and embryonic cell fate decisions: a great collaboration with Florian Halbritter, spearheaded by Ingrid Saldana-Guerrero and Luis Montano-Gutierrez (all Mastodon-less, I think) #devbiol #Devbiol #stemcell #cancer #neuroblastoma #neuralcrest
https://www.biorxiv.org/content/10.1101/2022.11.21.515753v1

Referenced link: https://medicalxpress.com/news/2022-11-cell-behavior-resistance-neuroblastoma.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2022-11-cell-behavior-resistance-neuroblastoma.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/medical_xpress/status/1591100785454350337#m

RT by @physorg_com: Altered cell behavior behind resistance in #neuroblastoma @ScienceAdvances https://www.science.org/doi/10.1126/sciadv.abq4617 https://medicalxpress.com/news/2022-11-cell-behavior-resistance-neuroblastoma.html

#introduction Long overdue, but here goes:

I'm Arjan, during working hours researching a specific children's #cancer, #neuroblastoma, mostly by means of #bioinformatics analyses of #sequencing data; right now lots of #scRNAseq . I might occasionally toot about this, or related stuff like #immunology , #rstats , #atherosclerosis and other scientific interests and/or fields that I've worked in.

Referenced link: https://medicalxpress.com/news/2022-08-achilles-heel-neuroblastoma.html
Discuss on https://discu.eu/q/https://medicalxpress.com/news/2022-08-achilles-heel-neuroblastoma.html

Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/medical_xpress/status/1559886273896235011#m

RT by @physorg_com: Researchers identify an Achilles' heel in #neuroblastoma @BCMHouston @NatureComms https://www.nature.com/articles/s41467-022-31331-2 https://medicalxpress.com/news/2022-08-achilles-heel-neuroblastoma.html