In our new preprint we characterise neuropeptide signalling in the cnidarian #Nematostella.
https://www.biorxiv.org/content/10.1101/2023.07.03.547448v1
Daniel Thiel and Luis Yanez-Guerra screened 64 neuropeptides against 161 G-protein coupled receptors (#GPCR) and found activating peptide ligands for 31 receptors.
#cnidaria #neuropeptide #evolution #neuroscience

Uncovering secrets of #seacucumbers! Suwansa-Ard et al., 2018 use next-gen sequencing & SequenceServer 🧬 to analyse #neuropeptide #genes, shedding light on their signalling systems. Valuable insights for improving #aquaculture in these species!

#BLASTfromthepast #bioinformatics

For #neuropeptide afficionados:
Interesting new paper from James Checco's lab on two #Aplysia #allatotropin / #orexin receptors, one activated by a D-peptide the other one by an L-peptide.
Conversion of an L-stereoisomer to a D-stereoisomer is a big mystery in peptide biology - but it matters for rec specificity and lifetime.
https://www.pnas.org/doi/10.1073/pnas.2217604120

New research from Herring lab researchers shows that routine testing for the #stress hormone #Neuropeptide Y (#NPY) in the hours after a #heart attack has the potential to save thousands of lives.
#HeartAttack #Medical #sflorg
https://www.sflorg.com/2023/01/med01312301.html

Application for participation now open for the Janelia "Neuropeptide Signaling: Bridging Cell Biology, Neurophysiology, and Behavior" #meeting in April 16 - 19, 2023.
Deadline: Jan 18
https://www.janelia.org/you-janelia/conferences/neuropeptide-signaling-bridging-cell-biology-neurophysiology-and-behavior
#Neuropeptide #Neurophysiology #Neuroscience

Excited to share our new manuscript on a novel #neuropeptide family that regulates #feeding across #evolution. Kudos to #Pat_TFrancisco for tackling this challenging project and coming up with the name #marmite. #homeostasis https://www.biorxiv.org/content/10.1101/2022.12.12.520095v3 Still figuring this space out. In the meantime if you want to check out the thread on the competing platform (links to the competition are allowed here?). https://twitter.com/RibeiroCarlitos/status/1605147211918196736 #drosophila

Our review with Stefan Gründer and Audrey Ortega Ramírez is out:

"Neuropeptides and DEG/ENaC ion channels: a relationship from mammals to cnidarians"

where we conclude based on structural comparisons and the #phylogeny of #neuropeptide systems that the interaction of DEG/ENaC channels with neuropeptides has diverse structural bases and many origins.

https://doi.org/10.1113/JP282309

NVG meeting now! Great start learning how C. elegance learn 🪱 by Isabel Beets
#animalbehaviour #learning #neuropeptide #NVG

NVG meeting now! Great start learning how C. elegance learn 🪱
#animalbehaviour #learning #neuropeptide #NVG

Oh hello there, my beautiful cells! #neuroscience #neuropeptide #locuscoeruleus #RNAscope #IHC