New pre-print from Voula Mili lab.
she suggests that mRNA localization and translation rate determine the localization of a protein which is found both in nucleus and cytoplasm.
I'll need to find time to dive it and read in detail.

#mRNA #mRNALocalization #translation #NuclearImport

https://www.biorxiv.org/content/10.1101/2023.04.24.538105v1

📣 💥 It took almost 12 years, but the final paper from my PhD is finally published @naturecomms
It is titled “RNA-controlled nucleocytoplasmic shuttling of mRNA decay factors regulates mRNA synthesis and a novel mRNA decay pathway” but the somewhat dry title hides a novel nuclear import mechanism that we discovered.
https://www.nature.com/articles/s41467-022-34417-z

A 🧵:

#mRNA #mRNADegradation #GeneExpression #yeast #nucleus #NuclearImport #RiboRegulation