https://www.cell.com/cell/fulltext/S0092-8674(23)00403-8 “#BNT162b4 encodes variant-conserved, immunogenic segments of the #SARSCoV2 #nucleocapsid, membrane, and ORF1ab proteins, targeting diverse #HLA alleles. BNT162b4 elicits polyfunctional #CD4+ and #CD8+ #Tcell responses from diverse #epitopes in animal models, alone or when co-administered with BNT162b2 while preserving spike-specific immunity. Importantly, we demonstrate that BNT162b4 protects hamsters from severe disease and reduces viral titers”
#bnt162b4 #SarsCoV2 #nucleocapsid #hla #cd4 #cd8 #TCell #epitopes
How Many Americans Have Had CoVid?
A large US government study now reports that 41.6% of American adults have had actual CoVid infections. #CoVid #antibody #testing #spike #nucleocapsid #pcr #hometesting
#COVID #antibody #testing #spike #nucleocapsid #pcr #hometesting