CellBioNews · @cellbionews
72 followers · 1597 posts · Server scientificnetwork.de
The EMBO Journal · @embojournal
451 followers · 200 posts · Server sciencemastodon.com
Extensive multivalent interactions between intrinsically disordered regions in the #BRCA1/#BARD1 #E3 #ligase and #nucleosome substrates facilitate #chromatin recruitment and contribute to histone H2A #ubiquitylation and #DNArepair
Sam Witus, Rachel Klevit, Weixing Zhao et al
https://www.embopress.org/doi/10.15252/embj.2023113565
#brca1 #e3 #ligase #nucleosome #chromatin #ubiquitylation #DNARepair
Biologic Models · @biologicmodels
11 followers · 58 posts · Server mstdn.science
#3Dprint of #Nucleosome in Complex COMPASS 6UH5 (the Complex of proteins Associated with Set1). Making these protein models feels like being a toy maker than it does a scientist.
@caseysteffen
https://buff.ly/3Xo6Dx3
Biologic Models · @biologicmodels
11 followers · 58 posts · Server mstdn.science
A nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of #DNA coiled around a core of histones. Explore the x-ray crystallography data and #3Dprint the #Nucleosome COMPASS Complex. #genetics #biotech #CRISP https://buff.ly/3Xo6Dx3 @mstdn.science
#DNA #3dprint #nucleosome #genetics #biotech #crisp
Biologic Models · @biologicmodels
11 followers · 58 posts · Server mstdn.science
A nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of #DNA coiled around a core of histones. Explore the x-ray crystallography data and #3Dprint the #Nucleosome COMPASS Complex. #genetics #biotech #CRISP https://buff.ly/3Xo6Dx3 @mstdn.science
#DNA #3dprint #nucleosome #genetics #biotech #crisp
Peer Community Journal · @PeerCommunityJournal
233 followers · 45 posts · Server ecoevo.social
A new article recommended by #PCIGenomics now published in Peer Community Journal, #genomics section! #Nucleosome patterns in four #plantpathogenicfungi with contrasted genome structures https://peercommunityjournal.org/articles/10.24072/pcjournal.227/ https://doi.org/10.24072/pcjournal.227
#PCIGenomics #Genomics #nucleosome #plantpathogenicfungi
Gene Regulation · @generegulation
901 followers · 245 posts · Server genomic.social#GeneRegulation digest week 2:
🧬DNA methylation atlas of human cell types
https://www.nature.com/articles/s41586-022-05580-6
🧬Evolution of #3Dchromatin organization (review)
https://www.sciencedirect.com/science/article/pii/S0959437X22001344
🧬#SMARCA5 (#SNF2H) maintains #nucleosome spacing near CTCF https://www.sciencedirect.com/science/article/pii/S1097276522011753 (in line with our Clarkson et al'2019 https://academic.oup.com/nar/article/47/21/11181/5609524)
🧬Loss of #epigenetic information as a cause of mammalian #aging https://www.sciencedirect.com/science/article/pii/S0092867422015707
🧬#Chromatin assembly of exogenous bacterial #chromosomes in yeast https://www.biorxiv.org/content/10.1101/2022.12.21.520625v2
#generegulation #3dchromatin #smarca5 #snf2h #nucleosome #epigenetic #aging #chromatin #Chromosomes
Biologic Models · @biologicmodels
11 followers · 58 posts · Server mstdn.science
A nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of #DNA coiled around a core of histones. Explore the x-ray crystallography data and #3Dprint the #Nucleosome COMPASS Complex. #genetics #biotech #CRISP https://buff.ly/3Xo6Dx3
#DNA #3dprint #nucleosome #genetics #biotech #crisp
Pierre Lindenbaum · @yokofakun
621 followers · 451 posts · Server genomic.social
#SingleCell multi-omics allows functional characterization of #structuralVariants https://www.nature.com/articles/s41587-022-01552-3 "We developed a computational method based on Strand-seq that combines #nucleosome occupancy and structural variation analysis in single cells to identify the functional effects of somatic structural variants in leukemia."
#singlecell #StructuralVariants #nucleosome
Gert Jan C. Veenstra · @gertjanveenstra
122 followers · 75 posts · Server mastodon.nl
On bioRxiv:
Nucleosomal DNA pull down with TFs
#genomics #epigenomics #nucleosome #chromatin #epigenetic
#epigenetic #chromatin #nucleosome #epigenomics #genomics
Gert Jan C. Veenstra · @gertjanveenstra
122 followers · 75 posts · Server mastodon.nl
A new histone modification, affecting H3K4me3
H3P16oh catalyzed by EGLN2 directs binding of KDM5A, resulting in a decrease of H3K4me3
#chromatin #nucleosome #generegulation #epigenetic
#epigenetic #generegulation #nucleosome #chromatin
elsasserlab · @simonelsasser
246 followers · 10 posts · Server mastodon.se
find us at http://elsaesserlab.org
#ScienceMastodon #devbio #embryo #chromatin #genome #nucleosome #epigenetics
#ScienceMastodon #devbio #embryo #chromatin #genome #nucleosome #epigenetics
Gert Jan C. Veenstra · @gertjanveenstra
122 followers · 75 posts · Server mastodon.nl#Introductions
I just moved my account from qoto.org to mastodon.nl. Nothing against the fine folks at Qoto, just a more recognizable address.
My interests are in:
- Epigenetic regulation of stem cells and lineage commitment
- Single cell omics and lineage trajectories of embryonic and heart development
- Gene-regulatory networks of development and differentiation
#epigenetics #nucleosome #genome #chromatin #Embryo #DevBio #introductions