The presence of spike-protein binding B cells in axillary lymph nodes even 15 weeks after Pfizer BNT162b2 vaccination, suggests SARS-CoV-2 protection could last years after immunisation.
- Turner 2021 Nature #observational
→ (summary) metajournal.com/34182569

Serum chloride level fluctuation in the first 72 h of ICU admission is independently associated with increased 30-day mortality.
- Kim 2019 BMCAnesthesiol #observational
→ metajournal.com/31101086

It is much more difficult to do an #observational cohort study well vs. an RCT. People forget that the #selection into cohort matters & that #causal assessments are more difficult (if outright impossible) with #cohorts, esp if you don't/won't grasp the mechanics of cohort generation.
#Biostatistics #epidemiology #clinicalresearch #clinicaltrials

Duration of rocuronium action directly correlates with BMI.
- Takahata 2018 EurJAnaesthesiol #observational
→ metajournal.com/29757926

The majority of anesthesia-related cardiac arrests are due to respiratory events.
- Hohn 2018 EurJAnaesthesiol #observational
→ metajournal.com/28922339

📢️Useful tool alert!📢️ Today at #ISHE2023 Jitka Lindová (Charles Uni.) and Marc Méhu (Webster Uni.) present a workshop on behavioural measurements in field and lab research. They introduce #ELAN #software: an annotation tool for audio🔊️ and video📽️ recordings. The first impression I have of this tool is really positive – plenty of options for customization to tailor the tool to your needs. If you sometimes code #behavioural #observational #data, check it out! https://archive.mpi.nl/tla/elan

Routine preoperative echocardiography before operative repair of hip fracture does not reduce mortality or postoperative complcayions.
- Yonekura 2019 Anesth.Analg. #observational
→ metajournal.com/30379676

Checklists for managing crises during cesarean section are practical to implement in low and middle-income countries, and significantly improve task completion in simulated emergencies.
- Alexander 2019 Anesth.Analg. #observational
→ metajournal.com/30379674

A greater relief in labor pain with epidural analgesia is associated with lower postpartum depression scores, although with less clinical significance than other risk factors.
- Lim 2018 Anesth.Analg. #observational
→ metajournal.com/29239949

Maternal desaturation is common during remifentanil PCA analgesia for labour.
- Messmer 2016 Anaesthesia #observational
→ metajournal.com/26617275

Cerebral perfusion is probably maintained during prone positioning for spinal surgery during stable hemodynamics.
- Bombardieri 2019 Anesth.Analg. #observational
→ metajournal.com/30418236

Focused cardiac ultrasound (FOCUS) can be management-altering in post-resuscitation care following cardiac arrest.
- Elfwén 2019 Resuscitation #observational
→ metajournal.com/31279947

Chewing gum for one hour does not change gastric fluid volume.
- Valencia 2019 JClinAnesth #observational
→ metajournal.com/30731390

Hypercapnia events are common in women receiving 150 mcg intrathecal morphine for cesarean delivery, although clinical significance is uncertain.
- Bauchat 2017 Anesth.Analg. #observational
→ metajournal.com/28099291

Intending to deliver with labour epidural analgesia and then receiving a labour epidural is associated with slightly lower rate of postnatal depression.
- Orbach-Zinger 2018 Anesth.Analg. #observational
→ metajournal.com/28930940

Simple measurement of cortical functional connectivity will not be enough to assess adequacy of general anesthesia.
- Vlisides 2019 Anesthesiology #observational
→ metajournal.com/30946057

Delayed or inadequate labour neuraxial analgesia, and analgesia-related side effects, are associated with maternal dissatisfaction with obstetric anaesthetic care.
- Yurashevich 2019 Anaesthesia #observational
→ metajournal.com/31264207

Invasive Respiratory or Vasopressor Support is a useful surrogate perioperative marker for prolonged hospital stay, and both in-hospital and long-term survival.
- Mizota 2019 Anesth.Analg. #observational
→ metajournal.com/31425207

Recent cannabis use is associated with greater post-operative pain and poorer sleep, after major orthopedic surgery.
- Liu 2019 Anesth.Analg. #observational
→ metajournal.com/31425232

Intraoperative and postoperative hypotension are both associated with postoperative delirium among patients admitted to ICU.
- Maheshwari 2020 Anesth.Analg. #observational
→ metajournal.com/31725024