How do cancer-specific chromosome gains/losses contribute to #oncogenesis?
Susanne Lens and collaborators at UMC Utrecht describe a #kinesin-based strategy for inducing #mitotic #missegregation of selected #chromosomes, as tool for modeling specific #aneuploidies

https://www.embopress.org/doi/10.15252/embj.2022111559

RT @lipidchronicles
Ablation of sphingosine kinase 2 suppresses fatty liver-associated hepatocellular carcinoma via downregulation of ceramide transfer protein https://buff.ly/3zNWn7Y (@Nature_NPJ @NaturePortfolio #Oncogenesis)