Bose-Einstein-Kondensat · @MWNautilus
99 followers · 10 posts · Server mstdn.social
#optoPlate-96: An #OpenSource #GUI to design high-throughput #optogenetic experiments with the optoPlate-96:
Paper: https://doi.org/10.1038/s41596-020-0349-x
GitHub: https://github.com/WeberSynBioLab/optoConfig-96
#DIYbio #lab #instruments #Python #Arduino #fluorescence #PlateReader #optogenetics
#optogenetics #platereader #fluorescence #Arduino #Python #instruments #lab #diybio #optogenetic #GUI #OpenSource #optoplate
Bose-Einstein-Kondensat · @MWNautilus
99 followers · 10 posts · Server mstdn.social
#optoPlateReader (#oPR): An #OpenSource #Arduino-controlled #PlateReader that allows #automated #optogenetic stimulation & #spectroscopy in each well of a 96-well plate:
https://doi.org/10.1101/2022.07.13.499906
#DIYbio #biohacking #chemistry #lab #instruments #fluorescence #OD #LED #python #GUI
#GUI #Python #led #od #fluorescence #instruments #lab #chemistry #biohacking #diybio #spectroscopy #optogenetic #Automated #platereader #Arduino #OpenSource #OPR #optoplatereader
Gaspar Jekely · @jekely
366 followers · 1 posts · Server biologists.social
Our favourite #Platynereis #opsin now in the mammalian brain as a new #optogenetic tool!
"Here we ... found that the Platynereis dumerilii ciliary opsin ... is an efficient, versatile, light-activated bistable GPCR that can suppress synaptic transmission in mammalian neurons with high temporal precision in-vivo "
#platynereis #opsin #optogenetic #neuroscience #gpcr
Jonas Wietek :vibing: · @JWietek
328 followers · 180 posts · Server mstdn.science🚨#Optogenetic preprint alert🚨
Check out PdCO:
Light-controlled inhibition of synaptic transmission via the inhibitory #GPCR pathway. #optogenetics #neuroscience
Link:
#optogenetic #GPCR #optogenetics #neuroscience
The vOICe vision · @seeingwithsound
374 followers · 1152 posts · Server mas.to
A clinically viable approach to restoring visual function using #optogenetic #gene #therapy https://www.cell.com/molecular-therapy-family/methods/fulltext/S2329-0501(23)00067-0 "Chronos-expressing vectors were efficacious over a broad range of vector doses and stimulating light intensities, and were well tolerated"; #blindness
#blindness #therapy #gene #optogenetic
Brian Knutson · @knutson_brain
664 followers · 1115 posts · Server sfba.social
Ingenious #optogenetic manipulation of the heart and brain (i.e., posterior insula) shows that heart rate can modulate, but does not mediate, uncertainty-based arousal (in mice, by my clever #stanford colleagues):
https://www.nature.com/articles/s41586-023-05748-8
seeingwithsound · @seeingwithsound
335 followers · 704 posts · Server mas.toA thin-film #optogenetic #visual #prosthesis https://www.biorxiv.org/content/10.1101/2023.01.31.526482v1.full.pdf by @maxhodak et al., and note the remark on the bird site https://twitter.com/GhezziLab/status/1621956605095862274 https://infoscience.epfl.ch/record/269141/files/%20Optic%20nerve%20intraneural%20stimulation%20allows%20selective%20visual%20cortex%20activation%20.pdf #BCI #NeuroTech
#neurotech #bci #prosthesis #visual #optogenetic
seeingwithsound · @seeingwithsound
262 followers · 378 posts · Server mas.to
#Optogenetic therapy for visual restoration https://www.mdpi.com/1422-0067/23/23/15041
Mark Baxter 🏳️🌈💉🧂 · @markgbaxter
561 followers · 101 posts · Server mastodon.socialI mean, count the number of publications with successful #chemogenetic manipulations versus successful #optogenetic manipulations that influence behavior in NHPs and draw your own conclusions about which is a more fruitful strategy for neuromodulation
Joachim Goedhart · @JoachimGoedhart
664 followers · 210 posts · Server mas.to
New #preprint from our lab 🎉 :toot:
We report an iLID-nanobody fusion to enable #optogenetic recruitment to #GFP. This is potentially interesting when you already have a cell line or model organism expressing a GFP fusion protein.
https://www.biorxiv.org/content/10.1101/2022.11.24.517828v2
Joachim Goedhart · @JoachimGoedhart
890 followers · 320 posts · Server mas.toNew #preprint from our lab 🎉 :toot:
We report an iLID-nanobody fusion to enable #optogenetic recruitment to #GFP. This is potentially interesting when you already have a cell line or model organism expressing a GFP fusion protein.
https://www.biorxiv.org/content/10.1101/2022.11.24.517828v2
